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microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP.
Zhang X, Chapat C, Wang P, Choi JH, Li Q, Luo J, Wiebe S, Kim SH, Robichaud N, Karam IF, Dai D, Hackett AP, Lin R, Alain T, Yang L, Jafarnejad SM, Sonenberg N. Zhang X, et al. Among authors: luo j. Mol Cell. 2021 Mar 18;81(6):1187-1199.e5. doi: 10.1016/j.molcel.2021.01.030. Epub 2021 Feb 12. Mol Cell. 2021. PMID: 33581076 Free article.
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N. Xu Z, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204539119. doi: 10.1073/pnas.2204539119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878012 Free PMC article.
The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses.
Ladak RJ, Choi JH, Luo J, Chen OJ, Mahmood N, He AJ, Naeli P, Snell PH, Bayani E, Hoang HD, Alain T, Teodoro JG, Wang J, Zhang X, Jafarnejad SM, Sonenberg N. Ladak RJ, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2413018121. doi: 10.1073/pnas.2413018121. Epub 2024 Nov 19. Proc Natl Acad Sci U S A. 2024. PMID: 39560640 Free PMC article.
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