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Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS.
Mahida RY, Lax S, Bassford CR, Scott A, Parekh D, Hardy RS, Naidu B, Matthay MA, Stewart PM, Cooper MC, Perkins GD, Thickett DR. Mahida RY, et al. Among authors: hardy rs. Front Immunol. 2023 Apr 27;14:1159831. doi: 10.3389/fimmu.2023.1159831. eCollection 2023. Front Immunol. 2023. PMID: 37180160 Free PMC article.
Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β.
O'Neil JD, Bolimowska OO, Clayton SA, Tang T, Daley KK, Lara-Reyna S, Warner J, Martin CS, Mahida RY, Hardy RS, Arthur JSC, Clark AR. O'Neil JD, et al. Among authors: hardy rs. Front Immunol. 2023 Oct 24;14:1190261. doi: 10.3389/fimmu.2023.1190261. eCollection 2023. Front Immunol. 2023. PMID: 37942320 Free PMC article.
Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis.
Martin CS, Crastin A, Sagmeister MS, Kalirai MS, Turner JD, MacDonald L, Kurowska-Stolarska M, Scheel-Toellner D, Taylor AE, Gilligan LC, Storbeck K, Price M, Gorvin CM, A F, Mahida R, Clark AR, Jones SW, Raza K, Hewison M, Hardy RS. Martin CS, et al. Among authors: hardy rs. J Autoimmun. 2024 Jul;147:103263. doi: 10.1016/j.jaut.2024.103263. Epub 2024 Jun 8. J Autoimmun. 2024. PMID: 38851089 Free article.
Inflammation and Skeletal Muscle Wasting During Cachexia.
Webster JM, Kempen LJAP, Hardy RS, Langen RCJ. Webster JM, et al. Among authors: hardy rs. Front Physiol. 2020 Nov 19;11:597675. doi: 10.3389/fphys.2020.597675. eCollection 2020. Front Physiol. 2020. PMID: 33329046 Free PMC article. Review.
47 results