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Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.
Theusch E, Ting FY, Qin Y, Stevens K, Naidoo D, King SM, Yang N, Orr J, Han BY, Cyster JG, Chen YI, Rotter JI, Krauss RM, Medina MW. Theusch E, et al. Among authors: naidoo d. bioRxiv [Preprint]. 2023 Jun 15:2023.06.14.544860. doi: 10.1101/2023.06.14.544860. bioRxiv. 2023. Update in: Genome Med. 2024 Jul 26;16(1):93. doi: 10.1186/s13073-024-01366-9 PMID: 37397985 Free PMC article. Updated. Preprint.
RHOA is a modulator of the cholesterol-lowering effects of statin.
Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. Among authors: naidoo d. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.
RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol.
Mitchel K, Theusch E, Cubitt C, Dosé AC, Stevens K, Naidoo D, Medina MW. Mitchel K, et al. Among authors: naidoo d. Circ Cardiovasc Genet. 2016 Jun;9(3):223-30. doi: 10.1161/CIRCGENETICS.115.001274. Epub 2016 Apr 12. Circ Cardiovasc Genet. 2016. PMID: 27071970 Free PMC article.
Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.
Medina MW, Bauzon F, Naidoo D, Theusch E, Stevens K, Schilde J, Schubert C, Mangravite LM, Rudel LL, Temel RE, Runz H, Krauss RM. Medina MW, et al. Among authors: naidoo d. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1917-23. doi: 10.1161/ATVBAHA.113.302806. Epub 2014 Jul 17. Arterioscler Thromb Vasc Biol. 2014. PMID: 25035345 Free PMC article.
SUGP1 is a novel regulator of cholesterol metabolism.
Kim MJ, Yu CY, Theusch E, Naidoo D, Stevens K, Kuang YL, Schuetz E, Chaudhry AS, Medina MW. Kim MJ, et al. Among authors: naidoo d. Hum Mol Genet. 2016 Jul 15;25(14):3106-3116. doi: 10.1093/hmg/ddw151. Epub 2016 May 20. Hum Mol Genet. 2016. PMID: 27206982 Free PMC article.
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM. Mangravite LM, et al. Among authors: naidoo d. Nature. 2013 Oct 17;502(7471):377-80. doi: 10.1038/nature12508. Epub 2013 Aug 28. Nature. 2013. PMID: 23995691 Free PMC article.
A polymorphism in HLA-G modifies statin benefit in asthma.
Naidoo D, Wu AC, Brilliant MH, Denny J, Ingram C, Kitchner TE, Linneman JG, McGeachie MJ, Roden DM, Shaffer CM, Shah A, Weeke P, Weiss ST, Xu H, Medina MW. Naidoo D, et al. Pharmacogenomics J. 2015 Jun;15(3):272-7. doi: 10.1038/tpj.2014.55. Epub 2014 Sep 30. Pharmacogenomics J. 2015. PMID: 25266681 Free PMC article.
394 results