Schorn TW - Search Results

1

Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.

Boger J, Payne LS, Perlow DS, Lohr NS, Poe M, Blaine EH, Ulm EH, Schorn TW, LaMont BI, Lin TY, et al. Boger J, et al. Among authors: schorn tw. J Med Chem. 1985 Dec;28(12):1779-90. doi: 10.1021/jm00150a007. J Med Chem. 1985. PMID: 3906131

2

Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics.

Williams PD, Perlow DS, Payne LS, Holloway MK, Siegl PK, Schorn TW, Lynch RJ, Doyle JJ, Strouse JF, Vlasuk GP, et al. Williams PD, et al. Among authors: schorn tw. J Med Chem. 1991 Mar;34(3):887-900. doi: 10.1021/jm00107a004. J Med Chem. 1991. PMID: 2002469

3

Novel renin inhibitors containing the amino acid statine.

Boger J, Lohr NS, Ulm EH, Poe M, Blaine EH, Fanelli GM, Lin TY, Payne LS, Schorn TW, LaMont BI, Vassil TC, Stabilito II, Veber DF, Rich DH, Bopari AS. Boger J, et al. Among authors: schorn tw. Nature. 1983 May 5-11;303(5912):81-4. doi: 10.1038/303081a0. Nature. 1983. PMID: 6341856

4

Statine-containing renin inhibitor. Dissociation of blood pressure lowering and renin inhibition in sodium-deficient dogs.

Blaine EH, Schorn TW, Boger J. Blaine EH, et al. Among authors: schorn tw. Hypertension. 1984 Mar-Apr;6(2 Pt 2):I111-8. doi: 10.1161/01.hyp.6.2_pt_2.i111. Hypertension. 1984. PMID: 6373590

5

Design of proteolytically-stable, peptidal renin inhibitors and determination of their fate in vivo.

Boger J, Bennett CD, Payne LS, Ulm EH, Blaine EH, Homnick CF, Schorn TW, Lamont BI, Veber DF. Boger J, et al. Among authors: schorn tw. Regul Pept Suppl. 1985;4:8-13. doi: 10.1016/0167-0115(85)90210-1. Regul Pept Suppl. 1985. PMID: 3903877 No abstract available.

6

Comparison of renin and converting enzyme inhibition in sodium-deficient dogs.

Blaine EH, Nelson BJ, Seymour AA, Schorn TW, Sweet CS, Slater EE, Nussberger J, Boger J. Blaine EH, et al. Among authors: schorn tw. Hypertension. 1985 May-Jun;7(3 Pt 2):I66-71. doi: 10.1161/01.hyp.7.3_pt_2.i66. Hypertension. 1985. PMID: 2987127

7

Design of renin inhibitors containing conformationally restricted mimetics of the P1-P1' and P1 through P2' sites.

Williams PD, Payne LS, Perlow DS, Holloway MK, Siegl PK, Schorn TW, Lynch RJ, Doyle JJ, Strouse JF, Vlasuk GP, et al. Williams PD, et al. Among authors: schorn tw. Adv Exp Med Biol. 1991;306:325-34. doi: 10.1007/978-1-4684-6012-4_38. Adv Exp Med Biol. 1991. PMID: 1812722 No abstract available.

8

Acute hypotensive responses to peptide inhibitors of renin in conscious monkeys: an effect on blood pressure independent of plasma renin inhibition.

Schaffer LW, Schorn TW, Winquist RJ, Strouse JF, Payne L, Chakravarty PK, de Laszlo SE, tenBroeke J, Veber DF, Greenlee WJ, et al. Schaffer LW, et al. Among authors: schorn tw. J Hypertens. 1990 Mar;8(3):251-9. J Hypertens. 1990. PMID: 2159506

9

Renin inhibitors containing C-termini derived from mercaptoheterocycles.

Ashton WT, Cantone CL, Meurer LC, Tolman RL, Greenlee WJ, Patchett AA, Lynch RJ, Schorn TW, Strouse JF, Siegl PK. Ashton WT, et al. Among authors: schorn tw. J Med Chem. 1992 May 29;35(11):2103-12. doi: 10.1021/jm00089a023. J Med Chem. 1992. PMID: 1597860

10

The character of the atrial natriuretic response: pressure and volume effects.

Blaine EH, Heinel LA, Schorn TW, Marsh EA, Whinnery MA. Blaine EH, et al. Among authors: schorn tw. J Hypertens Suppl. 1986 Jun;4(2):S17-24. J Hypertens Suppl. 1986. PMID: 2941539

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