Unsworth AJ - Search Results

1

Pim Kinase Inhibition Disrupts CXCR4 Signalling in Megakaryocytes and Platelets by Reducing Receptor Availability at the Surface.

Nock SH, Blanco-Lopez MR, Stephenson-Deakin C, Jones S, Unsworth AJ. Nock SH, et al. Among authors: unsworth aj. Int J Mol Sci. 2024 Jul 11;25(14):7606. doi: 10.3390/ijms25147606. Int J Mol Sci. 2024. PMID: 39062849 Free PMC article.

2

Pim Kinases: Important Regulators of Cardiovascular Disease.

Nock S, Karim E, Unsworth AJ. Nock S, et al. Among authors: unsworth aj. Int J Mol Sci. 2023 Jul 18;24(14):11582. doi: 10.3390/ijms241411582. Int J Mol Sci. 2023. PMID: 37511341 Free PMC article. Review.

3

Differential Proteoglycan Expression in Atherosclerosis Alters Platelet Adhesion and Activation.

Drysdale A, Blanco-Lopez M, White SJ, Unsworth AJ, Jones S. Drysdale A, et al. Among authors: unsworth aj. Int J Mol Sci. 2024 Jan 12;25(2):950. doi: 10.3390/ijms25020950. Int J Mol Sci. 2024. PMID: 38256024 Free PMC article.

4

Cucurbitacins Elicit Anti-Platelet Activity via Perturbation of the Cytoskeleton and Integrin Function.

Kriek N, Nock SH, Sage T, Khalifa B, Bye AP, Mitchell JL, Thomson S, McLaughlin MG, Jones S, Gibbins JM, Unsworth AJ. Kriek N, et al. Among authors: unsworth aj. Thromb Haemost. 2022 Jul;122(7):1115-1129. doi: 10.1055/a-1788-5322. Epub 2022 Mar 4. Thromb Haemost. 2022. PMID: 35253142 Free PMC article.

5

The Contribution of Vascular Proteoglycans to Atherothrombosis: Clinical Implications.

Drysdale A, Unsworth AJ, White SJ, Jones S. Drysdale A, et al. Among authors: unsworth aj. Int J Mol Sci. 2023 Jul 24;24(14):11854. doi: 10.3390/ijms241411854. Int J Mol Sci. 2023. PMID: 37511615 Free PMC article. Review.

6

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.

Unsworth AJ, Bye AP, Sage T, Gaspar RS, Eaton N, Drew C, Stainer A, Kriek N, Volberding PJ, Hutchinson JL, Riley R, Jones S, Mundell SJ, Cui W, Falet H, Gibbins JM. Unsworth AJ, et al. Haematologica. 2021 Jul 1;106(7):1968-1978. doi: 10.3324/haematol.2019.223529. Haematologica. 2021. PMID: 32467143 Free PMC article.

7

Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib.

Bye AP, Unsworth AJ, Desborough MJ, Hildyard CAT, Appleby N, Bruce D, Kriek N, Nock SH, Sage T, Hughes CE, Gibbins JM. Bye AP, et al. Among authors: unsworth aj. Blood Adv. 2017 Dec 12;1(26):2610-2623. doi: 10.1182/bloodadvances.2017011999. eCollection 2017 Dec 12. Blood Adv. 2017. PMID: 29296914 Free PMC article.

8

Prevalence and prognostic significance of DNMT3A- and TET2- clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction.

Wang S, Hu S, Luo X, Bao X, Li J, Liu M, Lv Y, Zhao C, Zeng M, Chen X, Unsworth A, Jones S, Johnson TW, White SJ, Jia H, Yu B. Wang S, et al. EBioMedicine. 2022 Apr;78:103964. doi: 10.1016/j.ebiom.2022.103964. Epub 2022 Mar 24. EBioMedicine. 2022. PMID: 35339897 Free PMC article.

9

Delineating Zinc Influx Mechanisms during Platelet Activation.

Kuravi SJ, Ahmed NS, Taylor KA, Capes EM, Bye A, Unsworth AJ, Gibbins JM, Pugh N. Kuravi SJ, et al. Among authors: unsworth aj. Int J Mol Sci. 2023 Jul 20;24(14):11689. doi: 10.3390/ijms241411689. Int J Mol Sci. 2023. PMID: 37511448 Free PMC article.

10

PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signaling and platelet function through up-regulation of protein kinase A activity.

Unsworth AJ, Kriek N, Bye AP, Naran K, Sage T, Flora GD, Gibbins JM. Unsworth AJ, et al. J Thromb Haemost. 2017 Feb;15(2):356-369. doi: 10.1111/jth.13578. Epub 2017 Feb 7. J Thromb Haemost. 2017. PMID: 27896950 Free PMC article.

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