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Page 1
Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.
Gupta K, Perkerson RB 3rd, Parsons TM, Angom R, Amerna D, Burgess JD, Ren Y, McLean PJ, Mukhopadhyay D, Vibhute P, Wszolek ZK, Zubair AC, Quiñones-Hinojosa A, Kanekiyo T. Gupta K, et al. Among authors: parsons tm. Stem Cell Res Ther. 2024 Jul 29;15(1):230. doi: 10.1186/s13287-024-03847-5. Stem Cell Res Ther. 2024. PMID: 39075600 Free PMC article.
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
Pottier C, Zhou X, Perkerson RB 3rd, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D,… See abstract for full author list ➔ Pottier C, et al. Among authors: parsons tm. Lancet Neurol. 2018 Jun;17(6):548-558. doi: 10.1016/S1474-4422(18)30126-1. Epub 2018 Apr 30. Lancet Neurol. 2018. PMID: 29724592 Free PMC article.
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
Nicholson AM, Zhou X, Perkerson RB, Parsons TM, Chew J, Brooks M, DeJesus-Hernandez M, Finch NA, Matchett BJ, Kurti A, Jansen-West KR, Perkerson E, Daughrity L, Castanedes-Casey M, Rousseau L, Phillips V, Hu F, Gendron TF, Murray ME, Dickson DW, Fryer JD, Petrucelli L, Rademakers R. Nicholson AM, et al. Among authors: parsons tm. Acta Neuropathol Commun. 2018 May 31;6(1):42. doi: 10.1186/s40478-018-0545-x. Acta Neuropathol Commun. 2018. PMID: 29855382 Free PMC article.
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.
Zhou X, Nicholson AM, Ren Y, Brooks M, Jiang P, Zuberi A, Phuoc HN, Perkerson RB, Matchett B, Parsons TM, Finch NA, Lin W, Qiao W, Castanedes-Casey M, Phillips V, Librero AL, Asmann Y, Bu G, Murray ME, Lutz C, Dickson DW, Rademakers R. Zhou X, et al. Among authors: parsons tm. Brain. 2020 Jun 1;143(6):1905-1919. doi: 10.1093/brain/awaa141. Brain. 2020. PMID: 32504082 Free PMC article.
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4.
Oue H, Yamazaki Y, Qiao W, Yuanxin C, Ren Y, Kurti A, Shue F, Parsons TM, Perkerson RB, Kawatani K, Wang N, Starling SC, Roy B, Mosneag IE, Aikawa T, Holm ML, Liu CC, Inoue Y, Sullivan PM, Asmann YW, Kim BY, Bu G, Kanekiyo T. Oue H, et al. Among authors: parsons tm. JCI Insight. 2023 Apr 10;8(7):e163822. doi: 10.1172/jci.insight.163822. JCI Insight. 2023. PMID: 37036005 Free PMC article.
A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models.
Burgess JD, Amerna D, Norton ES, Parsons TM, Perkerson RB 3rd, Faroqi AH, Wszolek ZK, Cazares HG, Kanekiyo T, Delenclos M, McLean PJ. Burgess JD, et al. Among authors: parsons tm. Res Sq [Preprint]. 2023 May 3:rs.3.rs-2838195. doi: 10.21203/rs.3.rs-2838195/v1. Res Sq. 2023. Update in: Stem Cell Res Ther. 2023 Oct 5;14(1):289. doi: 10.1186/s13287-023-03515-0. PMID: 37205579 Free PMC article. Updated. Preprint.
ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism.
Kawatani K, Holm ML, Starling SC, Martens YA, Zhao J, Lu W, Ren Y, Li Z, Jiang P, Jiang Y, Baker SK, Wang N, Roy B, Parsons TM, Perkerson RB 3rd, Bao H, Han X, Bu G, Kanekiyo T. Kawatani K, et al. Among authors: parsons tm. Mol Psychiatry. 2024 Mar;29(3):809-819. doi: 10.1038/s41380-023-02372-w. Epub 2023 Dec 22. Mol Psychiatry. 2024. PMID: 38135757 Free PMC article.
Human iPSC-derived MSCs induce neurotrophic effects and improve metabolic activity in acute neuronal injury models.
Kawatani K, Omana Suarez G, Perkerson RB 3rd, Parent EE, Nambara T, Knight JA, Parsons TM, Gupta K, Shue F, Alnobani A, Vibhute P, Cai H, Guerrero-Cázares H, Copland JA 3rd, Quiñones-Hinojosa A, Kanekiyo T. Kawatani K, et al. Among authors: parsons tm. J Neurosci. 2024 Nov 4:e0606242024. doi: 10.1523/JNEUROSCI.0606-24.2024. Online ahead of print. J Neurosci. 2024. PMID: 39496487
25 results