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Page 1
Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors.
Metselaar DS, Meel MH, Goulding JR, du Chatinier A, Rigamonti L, Waranecki P, Geisemeyer N, de Gooijer MC, Breur M, Koster J, Veldhuijzen van Zanten SEM, Bugiani M, Franke NE, Reddy A, Wesseling P, Kaspers GJL, Hulleman E. Metselaar DS, et al. Among authors: breur m. Cell Rep Med. 2024 Sep 17;5(9):101700. doi: 10.1016/j.xcrm.2024.101700. Epub 2024 Aug 28. Cell Rep Med. 2024. PMID: 39208799 Free PMC article.
Structural Variants at the LMNB1 Locus: Deciphering Pathomechanisms in Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy.
Dimartino P, Zadorozhna M, Yumiceba V, Basile A, Cani I, Melo US, Henck J, Breur M, Tonon C, Lodi R, Brusco A, Pippucci T, Koufi FD, Boschetti E, Ramazzotti G, Manzoli L, Ratti S, Pinto E Vairo F, Delatycki MB, Vaula G, Cortelli P, Bugiani M, Spielmann M, Giorgio E. Dimartino P, et al. Among authors: breur m. Ann Neurol. 2024 Nov;96(5):855-870. doi: 10.1002/ana.27038. Epub 2024 Jul 30. Ann Neurol. 2024. PMID: 39078102
Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies.
Plug BC, Revers IM, Breur M, González GM, Timmerman JA, Meijns NRC, Hamberg D, Wagendorp J, Nutma E, Wolf NI, Luchicchi A, Mansvelder HD, van Til NP, van der Knaap MS, Bugiani M. Plug BC, et al. Among authors: breur m. Acta Neuropathol Commun. 2024 May 31;12(1):83. doi: 10.1186/s40478-024-01784-1. Acta Neuropathol Commun. 2024. PMID: 38822428 Free PMC article.
Proteomic dissection of vanishing white matter pathogenesis.
Man JHK, Zarekiani P, Mosen P, de Kok M, Debets DO, Breur M, Altelaar M, van der Knaap MS, Bugiani M. Man JHK, et al. Among authors: breur m. Cell Mol Life Sci. 2024 May 24;81(1):234. doi: 10.1007/s00018-024-05258-4. Cell Mol Life Sci. 2024. PMID: 38789799 Free PMC article.
Region-specific and age-related differences in astrocytes in the human brain.
Man JHK, Breur M, van Gelder CAGH, Marcon G, Maderna E, Giaccone G, Altelaar M, van der Knaap MS, Bugiani M. Man JHK, et al. Among authors: breur m. Neurobiol Aging. 2024 Aug;140:102-115. doi: 10.1016/j.neurobiolaging.2024.02.016. Epub 2024 May 18. Neurobiol Aging. 2024. PMID: 38763075 Free article.
Dominant CST3 variants cause adult onset leukodystrophy without amyloid angiopathy.
Bergner CG, Breur M, Soto-Bernardini MC, Schäfer L, Lier J, Le Duc D, Bundalian L, Schubert S, Brenner D, Kreuz FR, Schulte B, Waisfisz Q, Bugiani M, Köhler W, Sticht H, Abou Jamra R, van der Knaap MS. Bergner CG, et al. Among authors: breur m. Brain. 2024 Oct 3;147(10):3562-3572. doi: 10.1093/brain/awae085. Brain. 2024. PMID: 38489591
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amossé Q, Ceyzériat K, Badina AM, Kövari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM, Smith AM, Barnes SJ, Hampton DW, van der Valk P, Jacobson S, Howell OW, Baker D, Kipp M, Kaddatz H, Tournier BB, Millet P, Matthews PM, Moore CS, Amor S, Owen DR. Nutma E, et al. Among authors: breur m. Nat Commun. 2023 Aug 28;14(1):5247. doi: 10.1038/s41467-023-40937-z. Nat Commun. 2023. PMID: 37640701 Free PMC article.
Regional vulnerability of brain white matter in vanishing white matter.
Man JHK, van Gelder CAGH, Breur M, Molenaar D, Abbink T, Altelaar M, Bugiani M, van der Knaap MS. Man JHK, et al. Among authors: breur m. Acta Neuropathol Commun. 2023 Jun 22;11(1):103. doi: 10.1186/s40478-023-01599-6. Acta Neuropathol Commun. 2023. PMID: 37349783 Free PMC article.
Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophy.
Al-Saady M, Beerepoot S, Plug BC, Breur M, Galabova H, Pouwels PJW, Boelens JJ, Lindemans C, van Hasselt PM, Matzner U, Vanderver A, Bugiani M, van der Knaap MS, Wolf NI. Al-Saady M, et al. Among authors: breur m. Ann Clin Transl Neurol. 2023 Jul;10(7):1146-1159. doi: 10.1002/acn3.51796. Epub 2023 May 22. Ann Clin Transl Neurol. 2023. PMID: 37212343 Free PMC article.
44 results