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In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells.
Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH. Palanki R, et al. Among authors: alameh mg. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2400783121. doi: 10.1073/pnas.2400783121. Epub 2024 Jul 30. Proc Natl Acad Sci U S A. 2024. PMID: 39078677
siRNA Delivery with Chitosan: Influence of Chitosan Molecular Weight, Degree of Deacetylation, and Amine to Phosphate Ratio on in Vitro Silencing Efficiency, Hemocompatibility, Biodistribution, and in Vivo Efficacy.
Alameh M, Lavertu M, Tran-Khanh N, Chang CY, Lesage F, Bail M, Darras V, Chevrier A, Buschmann MD. Alameh M, et al. Biomacromolecules. 2018 Jan 8;19(1):112-131. doi: 10.1021/acs.biomac.7b01297. Epub 2017 Dec 28. Biomacromolecules. 2018. PMID: 29211954
Nanomaterial Delivery Systems for mRNA Vaccines.
Buschmann MD, Carrasco MJ, Alishetty S, Paige M, Alameh MG, Weissman D. Buschmann MD, et al. Among authors: alameh mg. Vaccines (Basel). 2021 Jan 19;9(1):65. doi: 10.3390/vaccines9010065. Vaccines (Basel). 2021. PMID: 33478109 Free PMC article. Review.
Ionizable lipid nanoparticles for in utero mRNA delivery.
Riley RS, Kashyap MV, Billingsley MM, White B, Alameh MG, Bose SK, Zoltick PW, Li H, Zhang R, Cheng AY, Weissman D, Peranteau WH, Mitchell MJ. Riley RS, et al. Among authors: alameh mg. Sci Adv. 2021 Jan 13;7(3):eaba1028. doi: 10.1126/sciadv.aba1028. Print 2021 Jan. Sci Adv. 2021. PMID: 33523869 Free PMC article.
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs.
Tombácz I, Laczkó D, Shahnawaz H, Muramatsu H, Natesan A, Yadegari A, Papp TE, Alameh MG, Shuvaev V, Mui BL, Tam YK, Muzykantov V, Pardi N, Weissman D, Parhiz H. Tombácz I, et al. Among authors: alameh mg. Mol Ther. 2021 Nov 3;29(11):3293-3304. doi: 10.1016/j.ymthe.2021.06.004. Epub 2021 Jun 4. Mol Ther. 2021. PMID: 34091054 Free PMC article.
89 results