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Page 1
Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle.
Caredio D, Koderman M, Frontzek KJ, Sorce S, Nuvolone M, Bremer J, Mariutti G, Schwarz P, Madrigal L, Mitrovic M, Sellitto S, Streichenberger N, Scheckel C, Aguzzi A. Caredio D, et al. Among authors: frontzek kj. PLoS Pathog. 2024 Sep 11;20(9):e1012552. doi: 10.1371/journal.ppat.1012552. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39259763 Free PMC article.
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis.
Losa M, Emmenegger M, De Rossi P, Schürch PM, Serdiuk T, Pengo N, Capron D, Bieli D, Bargenda N, Rupp NJ, Carta MC, Frontzek KJ, Lysenko V, Reimann RR, Schwarz P, Nuvolone M, Westermark GT, Nilsson KPR, Polymenidou M, Theocharides AP, Hornemann S, Picotti P, Aguzzi A. Losa M, et al. Among authors: frontzek kj. EMBO Mol Med. 2024 Sep;16(9):2024-2042. doi: 10.1038/s44321-024-00107-0. Epub 2024 Jul 30. EMBO Mol Med. 2024. PMID: 39080493 Free PMC article.
Genome wide association study of clinical duration and age at onset of sporadic CJD.
Hummerich H, Speedy H, Campbell T, Darwent L, Hill E, Collins S, Stehmann C, Kovacs GG, Geschwind MD, Frontzek K, Budka H, Gelpi E, Aguzzi A, van der Lee SJ, van Duijn CM, Liberski PP, Calero M, Sanchez-Juan P, Bouaziz-Amar E, Laplanche JL, Haïk S, Brandel JP, Mammana A, Capellari S, Poleggi A, Ladogana A, Pocchiari M, Zafar S, Booth S, Jansen GH, Areškevičiūtė A, Løbner Lund E, Glisic K, Parchi P, Hermann P, Zerr I, Appleby BS, Safar J, Gambetti P, Collinge J, Mead S. Hummerich H, et al. Among authors: frontzek k. PLoS One. 2024 Jul 26;19(7):e0304528. doi: 10.1371/journal.pone.0304528. eCollection 2024. PLoS One. 2024. PMID: 39079175 Free PMC article.
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, Hoop V, Delvendahl I, Pérez-Berlanga M, Gatta B, Panatta M, van der Bourg A, Bohaciakova D, Sharma P, De Vos L, Frontzek K, Aguzzi A, Lashley T, Robinson MD, Karayannis T, Mueller M, Hierlemann A, Polymenidou M. Hruska-Plochan M, et al. Among authors: frontzek k. Nature. 2024 Feb;626(8001):1073-1083. doi: 10.1038/s41586-024-07042-7. Epub 2024 Feb 14. Nature. 2024. PMID: 38355792 Free PMC article.
Whole-brain microscopy reveals distinct temporal and spatial efficacy of anti-Aβ therapies.
Kirschenbaum D, Dadgar-Kiani E, Catto F, Voigt FF, Trevisan C, Bichsel O, Shirani H, Nilsson KPR, Frontzek KJ, Paganetti P, Helmchen F, Lee JH, Aguzzi A. Kirschenbaum D, et al. Among authors: frontzek kj. EMBO Mol Med. 2023 Jan 11;15(1):e16789. doi: 10.15252/emmm.202216789. Epub 2022 Nov 16. EMBO Mol Med. 2023. PMID: 36382364 Free PMC article.
A conformational switch controlling the toxicity of the prion protein.
Frontzek K, Bardelli M, Senatore A, Henzi A, Reimann RR, Bedir S, Marino M, Hussain R, Jurt S, Meisl G, Pedotti M, Mazzola F, Siligardi G, Zerbe O, Losa M, Knowles T, Lakkaraju A, Zhu C, Schwarz P, Hornemann S, Holt MG, Simonelli L, Varani L, Aguzzi A. Frontzek K, et al. Nat Struct Mol Biol. 2022 Aug;29(8):831-840. doi: 10.1038/s41594-022-00814-7. Epub 2022 Aug 10. Nat Struct Mol Biol. 2022. PMID: 35948768 Free PMC article.
43 results