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155 results

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Page 1
A CAR enhancer increases the activity and persistence of CAR T cells.
Rakhshandehroo T, Mantri SR, Moravej H, Louis BBV, Salehi Farid A, Munaretto L, Regan K, Khan RMM, Wolff A, Farkash Z, Cong M, Kuhnast A, Nili A, Lee UJ, Allen HH, Berland L, Simkova E, Uslu SC, Tavakolpour S, Rowley JE, Codet E, Shahbazian H, Baral J, Pyrdol J, Jacobson CA, Nadeem O, Nia HT, Wucherpfennig KW, Rashidian M. Rakhshandehroo T, et al. Among authors: jacobson ca. Nat Biotechnol. 2024 Jul 30. doi: 10.1038/s41587-024-02339-4. Online ahead of print. Nat Biotechnol. 2024. PMID: 39079964
Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma.
Scholler N, Perbost R, Locke FL, Jain MD, Turcan S, Danan C, Chang EC, Neelapu SS, Miklos DB, Jacobson CA, Lekakis LJ, Lin Y, Ghobadi A, Kim JJ, Chou J, Plaks V, Wang Z, Xue A, Mattie M, Rossi JM, Bot A, Galon J. Scholler N, et al. Among authors: jacobson ca. Nat Med. 2022 Sep;28(9):1872-1882. doi: 10.1038/s41591-022-01916-x. Epub 2022 Aug 29. Nat Med. 2022. PMID: 36038629 Free PMC article.
Comparison of 2-year outcomes with CAR T cells (ZUMA-1) vs salvage chemotherapy in refractory large B-cell lymphoma.
Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Reagan PM, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Crump M, Kuruvilla J, Van Den Neste E, Farooq U, Navale L, DePuy V, Kim JJ, Gisselbrecht C. Neelapu SS, et al. Among authors: jacobson ca. Blood Adv. 2021 Oct 26;5(20):4149-4155. doi: 10.1182/bloodadvances.2020003848. Blood Adv. 2021. PMID: 34478487 Free PMC article.
Baseline Immune State and T-cell Clonal Kinetics are Associated with Durable Response to CAR-T Therapy in Large B-cell Lymphoma.
Maurer K, Grabski IN, Houot R, Gohil SH, Miura S, Redd RA, Lyu H, Lu W, Arihara Y, Budka J, McDonough M, Ansuinelli M, Reynolds CG, Jacene H, Li S, Livak KJ, Ritz J, Miles B, Mattie M, Neuberg DS, Irizarry RA, Armand P, Wu CJ, Jacobson CA. Maurer K, et al. Among authors: jacobson ca. Blood. 2024 Sep 6:blood.2024024381. doi: 10.1182/blood.2024024381. Online ahead of print. Blood. 2024. PMID: 39241199
Time to put the CAR-T before the horse.
Jacobson CA, Ritz J. Jacobson CA, et al. Blood. 2011 Nov 3;118(18):4761-2. doi: 10.1182/blood-2011-09-376137. Blood. 2011. PMID: 22053170 Free article. No abstract available.
155 results