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A CAR enhancer increases the activity and persistence of CAR T cells.
Rakhshandehroo T, Mantri SR, Moravej H, Louis BBV, Salehi Farid A, Munaretto L, Regan K, Khan RMM, Wolff A, Farkash Z, Cong M, Kuhnast A, Nili A, Lee UJ, Allen HH, Berland L, Simkova E, Uslu SC, Tavakolpour S, Rowley JE, Codet E, Shahbazian H, Baral J, Pyrdol J, Jacobson CA, Nadeem O, Nia HT, Wucherpfennig KW, Rashidian M. Rakhshandehroo T, et al. Among authors: pyrdol j. Nat Biotechnol. 2024 Jul 30. doi: 10.1038/s41587-024-02339-4. Online ahead of print. Nat Biotechnol. 2024. PMID: 39079964
A vaccine targeting resistant tumours by dual T cell plus NK cell attack.
Badrinath S, Dellacherie MO, Li A, Zheng S, Zhang X, Sobral M, Pyrdol JW, Smith KL, Lu Y, Haag S, Ijaz H, Connor-Stroud F, Kaisho T, Dranoff G, Yuan GC, Mooney DJ, Wucherpfennig KW. Badrinath S, et al. Among authors: pyrdol jw. Nature. 2022 Jun;606(7916):992-998. doi: 10.1038/s41586-022-04772-4. Epub 2022 May 25. Nature. 2022. PMID: 35614223 Free PMC article.
Cytokine conjugation to enhance T cell therapy.
Liu Y, Adu-Berchie K, Brockman JM, Pezone M, Zhang DKY, Zhou J, Pyrdol JW, Wang H, Wucherpfennig KW, Mooney DJ. Liu Y, et al. Among authors: pyrdol jw. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213222120. doi: 10.1073/pnas.2213222120. Epub 2022 Dec 28. Proc Natl Acad Sci U S A. 2023. PMID: 36577059 Free PMC article.
The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection.
Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. Moffett HF, et al. Among authors: pyrdol j. Nat Immunol. 2017 Jul;18(7):791-799. doi: 10.1038/ni.3755. Epub 2017 May 22. Nat Immunol. 2017. PMID: 28530712 Free PMC article.
29 results