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Lrp1 is a host entry factor for Rift Valley fever virus.
Ganaie SS, Schwarz MM, McMillen CM, Price DA, Feng AX, Albe JR, Wang W, Miersch S, Orvedahl A, Cole AR, Sentmanat MF, Mishra N, Boyles DA, Koenig ZT, Kujawa MR, Demers MA, Hoehl RM, Moyle AB, Wagner ND, Stubbs SH, Cardarelli L, Teyra J, McElroy A, Gross ML, Whelan SPJ, Doench J, Cui X, Brett TJ, Sidhu SS, Virgin HW, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Ganaie SS, et al. Among authors: hoehl rm. Cell. 2021 Sep 30;184(20):5163-5178.e24. doi: 10.1016/j.cell.2021.09.001. Epub 2021 Sep 23. Cell. 2021. PMID: 34559985 Free PMC article.
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice.
Schwarz MM, Ganaie SS, Feng A, Brown G, Yangdon T, White JM, Hoehl RM, McMillen CM, Rush RE, Connors KA, Cui X, Leung DW, Egawa T, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Among authors: hoehl rm. Sci Adv. 2023 Jul 14;9(28):eadh2264. doi: 10.1126/sciadv.adh2264. Epub 2023 Jul 14. Sci Adv. 2023. PMID: 37450601 Free PMC article.
Vaccine strains of Rift Valley fever virus exhibit attenuation at the maternal-fetal placental interface.
McMillen CM, Megli C, Radisic R, Skvarca LB, Hoehl RM, Boyles DA, McGaughey JJ, Bird BH, McElroy AK, Hartman AL. McMillen CM, et al. Among authors: hoehl rm. bioRxiv [Preprint]. 2024 Jun 1:2024.05.31.596800. doi: 10.1101/2024.05.31.596800. bioRxiv. 2024. Update in: J Virol. 2024 Aug 20;98(8):e0098324. doi: 10.1128/jvi.00983-24 PMID: 38854055 Free PMC article. Updated. Preprint.
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.
Schwarz MM, Price DA, Ganaie SS, Feng A, Mishra N, Hoehl RM, Fatma F, Stubbs SH, Whelan SPJ, Cui X, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Among authors: hoehl rm. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2204706119. doi: 10.1073/pnas.2204706119. Epub 2022 Aug 8. Proc Natl Acad Sci U S A. 2022. PMID: 35939689 Free PMC article.
A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease.
Nambulli S, Escriou N, Rennick LJ, Demers MJ, Tilston-Lunel NL, McElroy AK, Barbeau DJ, Crossland NA, Hoehl RM, Schrauf S, White AG, Borish HJ, Tomko JA, Frye LJ, Scanga CA, Flynn JL, Martin A, Gerke C, Hartman AL, Duprex WP. Nambulli S, et al. Among authors: hoehl rm. J Virol. 2024 May 14;98(5):e0176223. doi: 10.1128/jvi.01762-23. Epub 2024 Apr 2. J Virol. 2024. PMID: 38563762 Free PMC article.
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