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11 results

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Page 1
Loss of H3K9 trimethylation leads to premature aging.
Mrabti C, Yang N, Desdín-Micó G, Alonso-Calleja A, Vílchez-Acosta A, Pico S, Parras A, Piao Y, Schoenfeldt L, Luo S, Haghani A, Brooke R, Del Carmen Maza M, Branchina C, Maroun CY, von Meyenn F, Naveiras O, Horvath S, Sen P, Ocampo A. Mrabti C, et al. Among authors: desdin mico g. bioRxiv [Preprint]. 2024 Jul 24:2024.07.24.604929. doi: 10.1101/2024.07.24.604929. bioRxiv. 2024. PMID: 39091811 Free PMC article. Preprint.
In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A, Vílchez-Acosta A, Desdín-Micó G, Picó S, Mrabti C, Montenegro-Borbolla E, Maroun CY, Haghani A, Brooke R, Del Carmen Maza M, Rechsteiner C, Battiston F, Branchina C, Perez K, Horvath S, Bertelli C, Sempoux C, Ocampo A. Parras A, et al. Among authors: desdin mico g. Nat Aging. 2023 Dec;3(12):1509-1520. doi: 10.1038/s43587-023-00528-5. Epub 2023 Nov 27. Nat Aging. 2023. PMID: 38012287
Vitamin B12 emerges as key player during cellular reprogramming.
Vílchez-Acosta A, Desdín-Micó G, Ocampo A. Vílchez-Acosta A, et al. Among authors: desdin mico g. Nat Metab. 2023 Nov;5(11):1844-1845. doi: 10.1038/s42255-023-00917-5. Nat Metab. 2023. PMID: 37973898 No abstract available.
The role of T cells in age-related diseases.
Carrasco E, Gómez de Las Heras MM, Gabandé-Rodríguez E, Desdín-Micó G, Aranda JF, Mittelbrunn M. Carrasco E, et al. Among authors: desdin mico g. Nat Rev Immunol. 2022 Feb;22(2):97-111. doi: 10.1038/s41577-021-00557-4. Epub 2021 Jun 7. Nat Rev Immunol. 2022. PMID: 34099898 Review.
Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.
Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Redondo JM, Mittelbrunn M. Oller J, et al. Among authors: desdin mico g. Circulation. 2021 May 25;143(21):2091-2109. doi: 10.1161/CIRCULATIONAHA.120.051171. Epub 2021 Mar 12. Circulation. 2021. PMID: 33709773 Free PMC article.
Mitochondrial dysfunction defines T cell exhaustion.
Soto-Heredero G, Desdín-Micó G, Mittelbrunn M. Soto-Heredero G, et al. Among authors: desdin mico g. Cell Metab. 2021 Mar 2;33(3):470-472. doi: 10.1016/j.cmet.2021.02.010. Cell Metab. 2021. PMID: 33657392 Free article.
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence.
Desdín-Micó G, Soto-Heredero G, Aranda JF, Oller J, Carrasco E, Gabandé-Rodríguez E, Blanco EM, Alfranca A, Cussó L, Desco M, Ibañez B, Gortazar AR, Fernández-Marcos P, Navarro MN, Hernaez B, Alcamí A, Baixauli F, Mittelbrunn M. Desdín-Micó G, et al. Science. 2020 Jun 19;368(6497):1371-1376. doi: 10.1126/science.aax0860. Epub 2020 May 21. Science. 2020. PMID: 32439659
The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function.
Caravia XM, Fanjul V, Oliver E, Roiz-Valle D, Morán-Álvarez A, Desdín-Micó G, Mittelbrunn M, Cabo R, Vega JA, Rodríguez F, Fueyo A, Gómez M, Lobo-González M, Bueno H, Velasco G, Freije JMP, Andrés V, Ibáñez B, Ugalde AP, López-Otín C. Caravia XM, et al. Among authors: desdin mico g. PLoS Biol. 2018 Oct 22;16(10):e2006247. doi: 10.1371/journal.pbio.2006247. eCollection 2018 Oct. PLoS Biol. 2018. PMID: 30346946 Free PMC article.
Mitochondrial activity in T cells.
Desdín-Micó G, Soto-Heredero G, Mittelbrunn M. Desdín-Micó G, et al. Mitochondrion. 2018 Jul;41:51-57. doi: 10.1016/j.mito.2017.10.006. Epub 2017 Oct 12. Mitochondrion. 2018. PMID: 29032101 Free article. Review.
11 results