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In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma.
Nokin MJ, Darbo E, Richard E, San José S, de Hita S, Prouzet-Mauleon V, Turcq B, Gerardelli L, Crake R, Velasco V, Koopmansch B, Lambert F, Xue JY, Sang B, Horne J, Ziemons E, Villanueva A, Blomme A, Herfs M, Cataldo D, Calvayrac O, Porporato P, Nadal E, Lito P, Jänne PA, Ricciuti B, Awad MM, Ambrogio C, Santamaría D; Bolero Consortium. Nokin MJ, et al. Among authors: herfs m. Cell Rep Med. 2024 Aug 20;5(8):101663. doi: 10.1016/j.xcrm.2024.101663. Epub 2024 Aug 1. Cell Rep Med. 2024. PMID: 39094577 Free PMC article.
Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma.
Nokin MJ, Darbo E, Travert C, Drogat B, Lacouture A, San José S, Cabrera N, Turcq B, Prouzet-Mauleon V, Falcone M, Villanueva A, Wang H, Herfs M, Mosteiro M, Jänne PA, Pujol JL, Maraver A, Barbacid M, Nadal E, Santamaría D, Ambrogio C. Nokin MJ, et al. Among authors: herfs m. JCI Insight. 2020 Aug 6;5(15):e137869. doi: 10.1172/jci.insight.137869. JCI Insight. 2020. PMID: 32759499 Free PMC article.
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy.
Hubert P, Roncarati P, Demoulin S, Pilard C, Ancion M, Reynders C, Lerho T, Bruyere D, Lebeau A, Radermecker C, Meunier M, Nokin MJ, Hendrick E, Peulen O, Delvenne P, Herfs M. Hubert P, et al. Among authors: herfs m. J Immunother Cancer. 2021 Mar;9(3):e001966. doi: 10.1136/jitc-2020-001966. J Immunother Cancer. 2021. PMID: 33712445 Free PMC article.
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.
Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A. Nokin MJ, et al. Among authors: herfs m. Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7. Breast Cancer Res. 2019. PMID: 30674353 Free PMC article.
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.
El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, Körner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P. El-Hachem N, et al. Among authors: herfs m. Nat Cell Biol. 2024 Jul;26(7):1154-1164. doi: 10.1038/s41556-024-01439-2. Epub 2024 Jun 7. Nat Cell Biol. 2024. PMID: 38849541 Free PMC article.
A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine.
Herfs M, Roncarati P, Koopmansch B, Peulen O, Bruyere D, Lebeau A, Hendrick E, Hubert P, Poncin A, Penny W, Piazzon N, Monnien F, Guenat D, Mougin C, Prétet JL, Vuitton L, Segers K, Lambert F, Bours V, de Leval L, Valmary-Degano S, Quick CM, Crum CP, Delvenne P. Herfs M, et al. Br J Cancer. 2018 May;118(10):1302-1312. doi: 10.1038/s41416-018-0049-2. Epub 2018 Apr 27. Br J Cancer. 2018. PMID: 29700411 Free PMC article.
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.
Rademaker G, Hennequière V, Brohée L, Nokin MJ, Lovinfosse P, Durieux F, Gofflot S, Bellier J, Costanza B, Herfs M, Peiffer R, Bettendorff L, Deroanne C, Thiry M, Delvenne P, Hustinx R, Bellahcène A, Castronovo V, Peulen O. Rademaker G, et al. Among authors: herfs m. Oncogene. 2018 Aug;37(32):4398-4412. doi: 10.1038/s41388-018-0287-z. Epub 2018 May 3. Oncogene. 2018. PMID: 29720728 Free PMC article.
Cancer immunotherapy: it's time to better predict patients' response.
Pilard C, Ancion M, Delvenne P, Jerusalem G, Hubert P, Herfs M. Pilard C, et al. Among authors: herfs m. Br J Cancer. 2021 Sep;125(7):927-938. doi: 10.1038/s41416-021-01413-x. Epub 2021 Jun 10. Br J Cancer. 2021. PMID: 34112949 Free PMC article. Review.
94 results