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Page 1
Dendritic cell-intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity.
van der Zande HJ, Brombacher EC, Lambooij JM, Pelgrom LR, Zawistowska-Deniziak A, Patente TA, Heieis GA, Otto F, Ozir-Fazalalikhan A, Yazdanbakhsh M, Everts B, Guigas B. van der Zande HJ, et al. Among authors: brombacher ec. JCI Insight. 2023 Jun 8;8(11):e157948. doi: 10.1172/jci.insight.157948. JCI Insight. 2023. PMID: 37140993 Free PMC article.
A median fin derived from the lateral plate mesoderm and the origin of paired fins.
Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ. Tzung KW, et al. Among authors: brombacher ec. Nature. 2023 Jun;618(7965):543-549. doi: 10.1038/s41586-023-06100-w. Epub 2023 May 24. Nature. 2023. PMID: 37225983 Free PMC article.
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma.
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O'Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Prummel KD, et al. Among authors: brombacher ec. Nat Commun. 2022 Mar 30;13(1):1677. doi: 10.1038/s41467-022-29311-7. Nat Commun. 2022. PMID: 35354817 Free PMC article.
Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis.
Ludikhuize MC, Meerlo M, Gallego MP, Xanthakis D, Burgaya Julià M, Nguyen NTB, Brombacher EC, Liv N, Maurice MM, Paik JH, Burgering BMT, Rodriguez Colman MJ. Ludikhuize MC, et al. Among authors: brombacher ec. Cell Metab. 2020 Nov 3;32(5):889-900.e7. doi: 10.1016/j.cmet.2020.10.005. Cell Metab. 2020. PMID: 33147486 Free article.
A conserved regulatory program initiates lateral plate mesoderm emergence across chordates.
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. Prummel KD, et al. Among authors: brombacher ec. Nat Commun. 2019 Aug 26;10(1):3857. doi: 10.1038/s41467-019-11561-7. Nat Commun. 2019. PMID: 31451684 Free PMC article.
Circadian rhythms in mitochondrial respiration.
de Goede P, Wefers J, Brombacher EC, Schrauwen P, Kalsbeek A. de Goede P, et al. Among authors: brombacher ec. J Mol Endocrinol. 2018 Apr;60(3):R115-R130. doi: 10.1530/JME-17-0196. Epub 2018 Jan 29. J Mol Endocrinol. 2018. PMID: 29378772 Free PMC article. Review.