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Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis.
Keiser PT, Zhang W, Ricca M, Wacquiez A, Grimins A, Cencic R, Patten JJ, Shah P, Padilha E, Connor JH, Pelletier J, Lyons SM, Saeed M, Brown LE, Porco JA Jr, Davey RA. Keiser PT, et al. Among authors: grimins a. Antiviral Res. 2024 Oct;230:105976. doi: 10.1016/j.antiviral.2024.105976. Epub 2024 Aug 6. Antiviral Res. 2024. PMID: 39117283