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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity.
Ngiow SF, Manne S, Huang YJ, Azar T, Chen Z, Mathew D, Chen Q, Khan O, Wu JE, Alcalde V, Flowers AJ, McClain S, Baxter AE, Kurachi M, Shi J, Huang AC, Giles JR, Sharpe AH, Vignali DAA, Wherry EJ. Ngiow SF, et al. Among authors: kurachi m. Cell. 2024 Aug 8;187(16):4336-4354.e19. doi: 10.1016/j.cell.2024.07.018. Cell. 2024. PMID: 39121847
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Beltra JC, Abdel-Hakeem MS, Manne S, Zhang Z, Huang H, Kurachi M, Su L, Picton L, Ngiow SF, Muroyama Y, Casella V, Huang YJ, Giles JR, Mathew D, Belman J, Klapholz M, Decaluwe H, Huang AC, Berger SL, Garcia KC, Wherry EJ. Beltra JC, et al. Among authors: kurachi m. Immunity. 2023 Dec 12;56(12):2699-2718.e11. doi: 10.1016/j.immuni.2023.11.005. Immunity. 2023. PMID: 38091951
Japanese clinical practice guidelines for aspiration and pharyngeal residual assessment during eating and swallowing for nursing care.
Sugama J, Ishibasi M, Ota E, Kamakura Y, Saitoh E, Sanada H, Nakayama T, Nomura T, Yamada M, Nakagami G, Sato N, Shibata S, Hase T, Fukada J, Miki T, Arita M, Urai T, Okawa Y, Kitamura A, Dai M, Takahashi T, Tamai N, Tobita I, Noguchi H, Matsumoto M, Miura Y, Mukai K, Mugita Y, Yoshida M, Kurachi M, Shirasaka T, Yamane Y. Sugama J, et al. Among authors: kurachi m. Jpn J Nurs Sci. 2022 Oct;19(4):e12496. doi: 10.1111/jjns.12496. Epub 2022 Jun 18. Jpn J Nurs Sci. 2022. PMID: 35715990
Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET.
Shirasaki T, Yamagoe S, Shimakami T, Murai K, Imamura R, Ishii KA, Takayama H, Matsumoto Y, Tajima-Shirasaki N, Nagata N, Shimizu R, Yamanaka S, Abe A, Omura H, Kawaguchi K, Okada H, Yamashita T, Yoshikawa T, Takimoto K, Taharaguchi M, Takatsuka S, Miyazaki Y, Tamai T, Tanabe Y, Kurachi M, Yamamoto Y, Kaneko S, Matsumoto K, Takamura T, Honda M. Shirasaki T, et al. Among authors: kurachi m. Nat Commun. 2022 Jun 8;13(1):3176. doi: 10.1038/s41467-022-30879-3. Nat Commun. 2022. PMID: 35676290 Free PMC article.
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection.
Stelekati E, Cai Z, Manne S, Chen Z, Beltra JC, Buchness LA, Leng X, Ristin S, Nzingha K, Ekshyyan V, Niavi C, Abdel-Hakeem MS, Ali MA, Drury S, Lau CW, Gao Z, Ban Y, Zhou SK, Ansel KM, Kurachi M, Jordan MS, Villarino AV, Ngiow SF, Wherry EJ. Stelekati E, et al. Among authors: kurachi m. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2106083119. doi: 10.1073/pnas.2106083119. Epub 2022 Apr 21. Proc Natl Acad Sci U S A. 2022. PMID: 35446623 Free PMC article.
Batf-mediated epigenetic control of effector CD8+ T cell differentiation.
Tsao HW, Kaminski J, Kurachi M, Barnitz RA, DiIorio MA, LaFleur MW, Ise W, Kurosaki T, Wherry EJ, Haining WN, Yosef N. Tsao HW, et al. Among authors: kurachi m. Sci Immunol. 2022 Feb 18;7(68):eabi4919. doi: 10.1126/sciimmunol.abi4919. Epub 2022 Feb 18. Sci Immunol. 2022. PMID: 35179948
392 results