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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity.
Ngiow SF, Manne S, Huang YJ, Azar T, Chen Z, Mathew D, Chen Q, Khan O, Wu JE, Alcalde V, Flowers AJ, McClain S, Baxter AE, Kurachi M, Shi J, Huang AC, Giles JR, Sharpe AH, Vignali DAA, Wherry EJ. Ngiow SF, et al. Among authors: shi j. Cell. 2024 Aug 8;187(16):4336-4354.e19. doi: 10.1016/j.cell.2024.07.018. Cell. 2024. PMID: 39121847
In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40.
Wu JE, Manne S, Ngiow SF, Baxter AE, Huang H, Freilich E, Clark ML, Lee JH, Chen Z, Khan O, Staupe RP, Huang YJ, Shi J, Giles JR, Wherry EJ. Wu JE, et al. Among authors: shi j. bioRxiv [Preprint]. 2023 Apr 17:2023.04.17.537229. doi: 10.1101/2023.04.17.537229. bioRxiv. 2023. Update in: Sci Immunol. 2023 Aug 25;8(86):eade3369. doi: 10.1126/sciimmunol.ade3369 PMID: 37131713 Free PMC article. Updated. Preprint.
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells.
Baxter AE, Huang H, Giles JR, Chen Z, Wu JE, Drury S, Dalton K, Park SL, Torres L, Simone BW, Klapholz M, Ngiow SF, Freilich E, Manne S, Alcalde V, Ekshyyan V, Berger SL, Shi J, Jordan MS, Wherry EJ. Baxter AE, et al. Among authors: shi j. Immunity. 2023 Jun 13;56(6):1320-1340.e10. doi: 10.1016/j.immuni.2023.05.008. Immunity. 2023. PMID: 37315535 Free article.
The Implications of CRISPR-Cas9 Genome Editing for IR.
Perkons NR, Sheth R, Ackerman D, Chen J, Saleh K, Hunt SJ, Nadolski GJ, Shi J, Gade TP. Perkons NR, et al. Among authors: shi j. J Vasc Interv Radiol. 2018 Sep;29(9):1264-1267.e1. doi: 10.1016/j.jvir.2018.02.027. J Vasc Interv Radiol. 2018. PMID: 30146193 Review. No abstract available.
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