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Page 1
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips J, Iturbe A, Erquizi A, Moore BD, Ryu D, Natu A, Dillon K, Torrellas J, Moran C, Ladd T, Afroz F, Islam T, Jagirdar J, Funk CC, Robinson M, Rangaraju S, Borchelt DR, Ertekin-Taner N, Kelly JW, Heppner FL, Johnson ECB, McFarland K, Levey AI, Prokop S, Seyfried NT, Golde TE. Levites Y, et al. Among authors: funk cc. Cell Rep Med. 2024 Aug 20;5(8):101669. doi: 10.1016/j.xcrm.2024.101669. Epub 2024 Aug 9. Cell Rep Med. 2024. PMID: 39127040 Free PMC article.
Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips JL, Iturbe A, Erqiuzi A, Moore BD, Ryu D, Natu A, Dillon KD, Torrellas J, Moran C, Ladd TB, Afroz KF, Islam T, Jagirdar J, Funk CC, Robinson M, Borchelt DR, Ertekin-Taner N, Kelly JW, Heppner FL, Johnson EC, McFarland K, Levey AL, Prokop S, Seyfried NT, Golde TE. Levites Y, et al. Among authors: funk cc. bioRxiv [Preprint]. 2023 Dec 7:2023.11.29.568318. doi: 10.1101/2023.11.29.568318. bioRxiv. 2023. Update in: Cell Rep Med. 2024 Aug 20;5(8):101669. doi: 10.1016/j.xcrm.2024.101669 PMID: 38076912 Free PMC article. Updated. Preprint.
APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics.
Ellis D, Watanabe K, Wilmanski T, Lustgarten MS, Korat AVA, Glusman G, Hadlock JJ, Fiehn O, Sebastiani P, Price ND, Hood L, Magis AT, Evans SJ, Pflieger L, Lovejoy JC, Gibbons SM, Funk CC, Baloni P, Rappaport N. Ellis D, et al. Among authors: funk cc. bioRxiv [Preprint]. 2024 Nov 12:2024.10.17.618322. doi: 10.1101/2024.10.17.618322. bioRxiv. 2024. PMID: 39605362 Free PMC article. Preprint.
Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.
Stojakovic A, Trushin S, Sheu A, Khalili L, Chang SY, Li X, Christensen T, Salisbury JL, Geroux RE, Gateno B, Flannery PJ, Dehankar M, Funk CC, Wilkins J, Stepanova A, O'Hagan T, Galkin A, Nesbitt J, Zhu X, Tripathi U, Macura S, Tchkonia T, Pirtskhalava T, Kirkland JL, Kudgus RA, Schoon RA, Reid JM, Yamazaki Y, Kanekiyo T, Zhang S, Nemutlu E, Dzeja P, Jaspersen A, Kwon YIC, Lee MK, Trushina E. Stojakovic A, et al. Among authors: funk cc. Commun Biol. 2024 Feb 26;7(1):234. doi: 10.1038/s42003-024-05810-9. Commun Biol. 2024. PMID: 38409374 Free PMC article. No abstract available.
Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth.
Mikheeva SA, Funk CC, Horner PJ, Rostomily RC, Mikheev AM. Mikheeva SA, et al. Among authors: funk cc. Mol Oncol. 2024 Mar;18(3):517-527. doi: 10.1002/1878-0261.13496. Epub 2023 Aug 7. Mol Oncol. 2024. PMID: 37507199 Free PMC article.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: funk cc. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
A metabolomic signature of the APOE2 allele.
Sebastiani P, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Lustgarten MS, Funk CC, Baloni P, Yao CH, Joshi S, Marron MM, Gurinovich A, Li M, Leshchyk A, Xiang Q, Andersen SL, Feitosa MF, Ukraintseva S, Soerensen M, Fiehn O, Ordovas JM, Haigis M, Monti S, Barzilai N, Milman S, Ferrucci L, Rappaport N, Patti GJ, Perls TT. Sebastiani P, et al. Among authors: funk cc. Geroscience. 2023 Feb;45(1):415-426. doi: 10.1007/s11357-022-00646-9. Epub 2022 Aug 23. Geroscience. 2023. PMID: 35997888 Free PMC article.
Dense data enables 21st century clinical trials.
Roach JC, Hodes JF, Funk CC, Shankle WR, Merrill DA, Hood L, Bramen J. Roach JC, et al. Among authors: funk cc. Alzheimers Dement (N Y). 2022 Jun 13;8(1):e12297. doi: 10.1002/trc2.12297. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35733645 Free PMC article. No abstract available.
Risk factors for severe COVID-19 differ by age for hospitalized adults.
Molani S, Hernandez PV, Roper RT, Duvvuri VR, Baumgartner AM, Goldman JD, Ertekin-Taner N, Funk CC, Price ND, Rappaport N, Hadlock JJ. Molani S, et al. Among authors: funk cc. Sci Rep. 2022 Apr 28;12(1):6568. doi: 10.1038/s41598-022-10344-3. Sci Rep. 2022. PMID: 35484176 Free PMC article.
47 results