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High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.
Jia X, Crawford JC, Gebregzabher D, Monson EA, Mettelman RC, Wan Y, Ren Y, Chou J, Novak T, McQuilten HA, Clarke M, Bachem A, Foo IJ, Fritzlar S, Carrera Montoya J, Trenerry AM, Nie S, Leeming MG, Nguyen THO, Kedzierski L, Littler DR, Kueh A, Cardamone T, Wong CY, Hensen L, Cabug A, Laguna JG, Agrawal M, Flerlage T, Boyd DF, Van de Velde LA, Habel JR, Loh L, Koay HF, van de Sandt CE, Konstantinov IE, Berzins SP, Flanagan KL, Wakim LM, Herold MJ, Green AM, Smallwood HS, Rossjohn J, Thwaites RS, Chiu C, Scott NE, Mackenzie JM, Bedoui S, Reading PC, Londrigan SL, Helbig KJ, Randolph AG, Thomas PG, Xu J, Wang Z, Chua BY, Kedzierska K. Jia X, et al. Among authors: kueh a. Cell. 2024 Aug 22;187(17):4586-4604.e20. doi: 10.1016/j.cell.2024.07.026. Epub 2024 Aug 12. Cell. 2024. PMID: 39137778 Free article.
MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway.
Sheikh BN, Phipson B, El-Saafin F, Vanyai HK, Downer NL, Bird MJ, Kueh AJ, May RE, Smyth GK, Voss AK, Thomas T. Sheikh BN, et al. Among authors: kueh aj. Oncogene. 2015 Nov 19;34(47):5807-20. doi: 10.1038/onc.2015.33. Epub 2015 Mar 16. Oncogene. 2015. PMID: 25772242
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM.
Rohrbeck L, Gong JN, Lee EF, Kueh AJ, Behren A, Tai L, Lessene G, Huang DC, Fairlie WD, Strasser A, Herold MJ. Rohrbeck L, et al. Among authors: kueh aj. Cell Death Differ. 2016 Dec;23(12):2054-2062. doi: 10.1038/cdd.2016.96. Epub 2016 Sep 30. Cell Death Differ. 2016. PMID: 27689874 Free PMC article.
DR5 and caspase-8 are dispensable in ER stress-induced apoptosis.
Glab JA, Doerflinger M, Nedeva C, Jose I, Mbogo GW, Paton JC, Paton AW, Kueh AJ, Herold MJ, Huang DC, Segal D, Brumatti G, Puthalakath H. Glab JA, et al. Among authors: kueh aj. Cell Death Differ. 2017 May;24(5):944-950. doi: 10.1038/cdd.2017.53. Epub 2017 Apr 14. Cell Death Differ. 2017. PMID: 28409774 Free PMC article.
98 results