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Page 1
Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Dar AA, Bezrookove V, Nosrati M, Ice R, Patino JM, Vaquero EM, Parrett B, Leong SP, Kim KB, Debs RJ, Soroceanu L, Miller JR 3rd, Desprez PY, Cleaver JE, Salomonis N, McAllister S, Kashani-Sabet M. Dar AA, et al. Among authors: desprez py. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206824119. doi: 10.1073/pnas.2206824119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969744 Free PMC article.
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY, McAllister S, Soroceanu L, Debs RJ, Salomonis N, Schadendorf D, Cleaver JE, Kashani-Sabet M. de Semir D, et al. Among authors: desprez py. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866840 Free PMC article.
Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma.
Ursu S, Majid S, Garger C, de Semir D, Bezrookove V, Desprez PY, McAllister S, Soroceanu L, Nosrati M, Yimam K, Hassoun A, Osorio R, Kashani-Sabet M, Dar AA. Ursu S, et al. Among authors: desprez py. Oncogenesis. 2019 Aug 13;8(8):42. doi: 10.1038/s41389-019-0153-z. Oncogenesis. 2019. PMID: 31409772 Free PMC article.
Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies.
Ice RJ, Chen M, Sidorov M, Le Ho T, Woo RWL, Rodriguez-Brotons A, Luu T, Jian D, Kim KB, Leong SP, Kim H, Kim A, Stone D, Nazarian A, Oh A, Tranah GJ, Nosrati M, de Semir D, Dar AA, Chang S, Desprez PY, Kashani-Sabet M, Soroceanu L, McAllister SD. Ice RJ, et al. Among authors: desprez py. Br J Cancer. 2020 Mar;122(5):648-657. doi: 10.1038/s41416-019-0696-y. Epub 2019 Dec 20. Br J Cancer. 2020. PMID: 31857724 Free PMC article.
PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
de Semir D, Bezrookove V, Nosrati M, Scanlon KR, Singer E, Judkins J, Rieken C, Wu C, Shen J, Schmudermayer C, Dar AA, Miller JR 3rd, Cobbs C, Yount G, Desprez PY, Debs RJ, Salomonis N, McAllister S, Cleaver JE, Soroceanu L, Kashani-Sabet M. de Semir D, et al. Among authors: desprez py. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9064-9073. doi: 10.1073/pnas.1914505117. Epub 2020 Apr 9. Proc Natl Acad Sci U S A. 2020. PMID: 32273388 Free PMC article.
Prevalence of Homologous Recombination Pathway Gene Mutations in Melanoma: Rationale for a New Targeted Therapeutic Approach.
Kim KB, Soroceanu L, de Semir D, Millis SZ, Ross J, Vosoughi E, Dar AA, Nosrati M, Desprez PY, Ice R, Chen M, Chetal K, Bhattacharjee A, Moretto J, Leong SP, Singer MI, Parrett BM, Minor DR, McAllister S, Miller JR 3rd, Salomonis N, Kashani-Sabet M. Kim KB, et al. Among authors: desprez py. J Invest Dermatol. 2021 Aug;141(8):2028-2036.e2. doi: 10.1016/j.jid.2021.01.024. Epub 2021 Feb 19. J Invest Dermatol. 2021. PMID: 33610559 Free article.
106 results