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IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma.
Bick F, Brenis Gómez CM, Lammens I, Van Moorleghem J, De Wolf C, Dupont S, Dumoutier L, Smith NP, Villani AC, Browaeys R, Alladina J, Haring AM, Medoff BD, Cho JL, Bigirimana R, Vieira J, Hammad H, Blanchetot C, Schuijs MJ, Lambrecht BN. Bick F, et al. Among authors: blanchetot c. J Allergy Clin Immunol. 2024 Nov;154(5):1129-1145. doi: 10.1016/j.jaci.2024.07.024. Epub 2024 Aug 13. J Allergy Clin Immunol. 2024. PMID: 39147327 Free article.
A reappraisal of IL-9 in inflammation and cancer.
Bick F, Blanchetot C, Lambrecht BN, Schuijs MJ. Bick F, et al. Among authors: blanchetot c. Mucosal Immunol. 2024 Oct 9:S1933-0219(24)00106-5. doi: 10.1016/j.mucimm.2024.10.003. Online ahead of print. Mucosal Immunol. 2024. PMID: 39389468 Free article. Review.
Development and characterization of agonistic antibodies targeting the Ig-like 1 domain of MuSK.
Lim JL, Augustinus R, Plomp JJ, Roya-Kouchaki K, Vergoossen DLE, Fillié-Grijpma Y, Struijk J, Thomas R, Salvatori D, Steyaert C, Blanchetot C, Vanhauwaert R, Silence K, van der Maarel SM, Verschuuren JJ, Huijbers MG. Lim JL, et al. Among authors: blanchetot c. Sci Rep. 2023 May 8;13(1):7478. doi: 10.1038/s41598-023-32641-1. Sci Rep. 2023. PMID: 37156800 Free PMC article.
ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome.
Vanhauwaert R, Oury J, Vankerckhoven B, Steyaert C, Jensen SM, Vergoossen DLE, Kneip C, Santana L, Lim JL, Plomp JJ, Augustinus R, Koide S, Blanchetot C, Ulrichts P, Huijbers MG, Silence K, Burden SJ. Vanhauwaert R, et al. Among authors: blanchetot c. Sci Transl Med. 2024 Sep 18;16(765):eado7189. doi: 10.1126/scitranslmed.ado7189. Epub 2024 Sep 18. Sci Transl Med. 2024. PMID: 39292800
Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy.
Budding K, Johansen LE, Van de Walle I, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, Bos JW, Jansen MD, Curial CAD, Silence K, de Haard H, Blanchetot C, Van de Ven L, Leusen JHW, Pasterkamp RJ, van den Berg LH, Hack CE, Boross P, van der Pol WL. Budding K, et al. Among authors: blanchetot c. Neurol Neuroimmunol Neuroinflamm. 2021 Nov 10;9(1):e1107. doi: 10.1212/NXI.0000000000001107. Print 2022 Jan. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 34759020 Free PMC article.
A Targetable, Noncanonical Signal Transducer and Activator of Transcription 3 Activation Induced by the Y-Less Region of IL-22 Receptor Orchestrates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice.
Michiels C, Puigdevall L, Cochez P, Achouri Y, Cheou P, Hendrickx E, Dauguet N, Blanchetot C, Dumoutier L. Michiels C, et al. Among authors: blanchetot c. J Invest Dermatol. 2021 Nov;141(11):2668-2678.e6. doi: 10.1016/j.jid.2021.04.016. Epub 2021 May 14. J Invest Dermatol. 2021. PMID: 33992648 Free article.
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy.
Bosco J, Zhou Z, Gabriëls S, Verma M, Liu N, Miller BK, Gu S, Lundberg DM, Huang Y, Brown E, Josiah S, Meiyappan M, Traylor MJ, Chen N, Asakura A, De Jonge N, Blanchetot C, de Haard H, Duffy HS, Keefe D. Bosco J, et al. Among authors: blanchetot c. Mol Ther Methods Clin Dev. 2021 Mar 23;21:369-381. doi: 10.1016/j.omtm.2021.03.013. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33898634 Free PMC article.
ARGX-117, a therapeutic complement inhibiting antibody targeting C2.
Van de Walle I, Silence K, Budding K, Van de Ven L, Dijkxhoorn K, de Zeeuw E, Yildiz C, Gabriels S, Percier JM, Wildemann J, Meeldijk J, Simons PJ, Boon L, Cox L, Holgate R, Urbanus R, Otten HG, Leusen JHW, Blanchetot C, de Haard H, Hack CE, Boross P. Van de Walle I, et al. Among authors: blanchetot c. J Allergy Clin Immunol. 2021 Apr;147(4):1420-1429.e7. doi: 10.1016/j.jaci.2020.08.028. Epub 2020 Sep 11. J Allergy Clin Immunol. 2021. PMID: 32926878 Free PMC article.
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Persson EK, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier JM, Deswarte K, Verschueren KHG, Dansercoer A, Gras D, Chanez P, Bachert C, Gonçalves A, Van Gorp H, De Haard H, Blanchetot C, Saunders M, Hammad H, Savvides SN, Lambrecht BN. Persson EK, et al. Among authors: blanchetot c. Science. 2019 May 24;364(6442):eaaw4295. doi: 10.1126/science.aaw4295. Science. 2019. PMID: 31123109
Increased expression of IL-24 in chronic spontaneous urticaria.
de Montjoye L, Herman A, Hendrickx E, Chéou P, Blanchetot C, Hofman E, Baeck M, Dumoutier L. de Montjoye L, et al. Among authors: blanchetot c. Allergy. 2019 Sep;74(9):1811-1813. doi: 10.1111/all.13832. Epub 2019 May 28. Allergy. 2019. PMID: 31006117 No abstract available.
44 results