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Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy.
Puumala E, Nabeela S, Thornburg CC, Grkovic T, Uppuluri P, Whitesell L, O'Keefe BR, Robbins N, Cowen LE. Puumala E, et al. Among authors: cowen le. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0119424. doi: 10.1128/aac.01194-24. Epub 2024 Sep 26. Antimicrob Agents Chemother. 2024. PMID: 39324798 Free PMC article.
Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL Jr, Robbins N, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: cowen le. Nat Commun. 2024 Aug 1;15(1):6440. doi: 10.1038/s41467-024-50740-z. Nat Commun. 2024. PMID: 39090082 Free PMC article. No abstract available.
Reply to: Lactobacillus species do not produce 1-acetyl-β-carboline.
MacAlpine J, Daniel-Ivad M, Atere D, Laflamme B, Robbins N, Navarre WW, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: cowen le. Nat Commun. 2024 Aug 1;15(1):6441. doi: 10.1038/s41467-024-50684-4. Nat Commun. 2024. PMID: 39090077 Free PMC article. No abstract available.
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation.
Knox J, Burns AR, Cooke B, Cammalleri SR, Kitner M, Ching J, Castelli JMP, Puumala E, Snider J, Koury E, Collins JB, Geissah S, Dowling JJ, Andersen EC, Stagljar I, Cowen LE, Lautens M, Zasada I, Roy PJ. Knox J, et al. Among authors: cowen le. Nat Commun. 2024 Jul 2;15(1):5529. doi: 10.1038/s41467-024-49738-4. Nat Commun. 2024. PMID: 38956039 Free PMC article.
168 results