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Page 1
Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk.
Mummey HM, Elison W, Korgaonkar K, Elgamal RM, Kudtarkar P, Griffin E, Benaglio P, Miller M, Jha A, Fox JEM, McCarthy MI, Preissl S, Gloyn AL, MacDonald PE, Gaulton KJ. Mummey HM, et al. Among authors: fox jem. bioRxiv [Preprint]. 2024 Aug 6:2024.08.03.606460. doi: 10.1101/2024.08.03.606460. bioRxiv. 2024. PMID: 39149326 Free PMC article. Preprint.
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.
Rottner AK, Ye Y, Navarro-Guerrero E, Rajesh V, Pollner A, Bevacqua RJ, Yang J, Spigelman AF, Baronio R, Bautista A, Thomsen SK, Lyon J, Nawaz S, Smith N, Wesolowska-Andersen A, Fox JEM, Sun H, Kim SK, Ebner D, MacDonald PE, Gloyn AL. Rottner AK, et al. Among authors: fox jem. Nat Genet. 2023 Jan;55(1):54-65. doi: 10.1038/s41588-022-01261-2. Epub 2022 Dec 21. Nat Genet. 2023. PMID: 36543916 Free PMC article.
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. Marcheva B, et al. Among authors: fox jem. Genes Dev. 2020 Aug 1;34(15-16):1089-1105. doi: 10.1101/gad.338178.120. Epub 2020 Jul 2. Genes Dev. 2020. PMID: 32616519 Free PMC article.
N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes.
Aichler M, Borgmann D, Krumsiek J, Buck A, MacDonald PE, Fox JEM, Lyon J, Light PE, Keipert S, Jastroch M, Feuchtinger A, Mueller NS, Sun N, Palmer A, Alexandrov T, Hrabe de Angelis M, Neschen S, Tschöp MH, Walch A. Aichler M, et al. Among authors: fox jem. Cell Metab. 2017 Jun 6;25(6):1334-1347.e4. doi: 10.1016/j.cmet.2017.04.012. Cell Metab. 2017. PMID: 28591636 Free article.
Functional plasticity of the human infant β-cell exocytotic phenotype.
Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AM, Korbutt G, MacDonald PE. Fox JE, et al. Endocrinology. 2013 Apr;154(4):1392-9. doi: 10.1210/en.2012-1934. Epub 2013 Feb 28. Endocrinology. 2013. PMID: 23449893
15 results