Zhang K - Search Results

1

Unified and Versatile Multiplex Platform for Expedited Method Development and Comprehensive Characterization of Therapeutic Peptides.

Goyon A, Wang S, Hofmann K, Nguyen DN, Yehl P, Zhang K. Goyon A, et al. Among authors: zhang k. Anal Chem. 2024 Aug 17. doi: 10.1021/acs.analchem.4c02941. Online ahead of print. Anal Chem. 2024. PMID: 39152894

2

Characterization and stability study of polysorbate 20 in therapeutic monoclonal antibody formulation by multidimensional ultrahigh-performance liquid chromatography-charged aerosol detection-mass spectrometry.

Li Y, Hewitt D, Lentz YK, Ji JA, Zhang TY, Zhang K. Li Y, et al. Among authors: zhang ty, zhang k. Anal Chem. 2014 May 20;86(10):5150-7. doi: 10.1021/ac5009628. Epub 2014 May 2. Anal Chem. 2014. PMID: 24749737

3

A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates.

Li Y, Gu C, Gruenhagen J, Zhang K, Yehl P, Chetwyn NP, Medley CD. Li Y, et al. Among authors: zhang k. J Chromatogr A. 2015 May 8;1393:81-8. doi: 10.1016/j.chroma.2015.03.027. Epub 2015 Mar 16. J Chromatogr A. 2015. PMID: 25818558

4

Compatibility study of a parenteral microdose polyethylene glycol formulation in medical devices and identification of degradation impurity by 2D-LC/MS.

Dai L, Yeh GK, Ran Y, Yehl P, Zhang K. Dai L, et al. Among authors: zhang k. J Pharm Biomed Anal. 2017 Apr 15;137:182-188. doi: 10.1016/j.jpba.2017.01.036. Epub 2017 Jan 18. J Pharm Biomed Anal. 2017. PMID: 28131057

5

Characterization of therapeutic oligonucleotides by liquid chromatography.

Goyon A, Yehl P, Zhang K. Goyon A, et al. Among authors: zhang k. J Pharm Biomed Anal. 2020 Apr 15;182:113105. doi: 10.1016/j.jpba.2020.113105. Epub 2020 Jan 20. J Pharm Biomed Anal. 2020. PMID: 32004766 Review.

6

Characterization of Antisense Oligonucleotide Impurities by Ion-Pairing Reversed-Phase and Anion Exchange Chromatography Coupled to Hydrophilic Interaction Liquid Chromatography/Mass Spectrometry Using a Versatile Two-Dimensional Liquid Chromatography Setup.

Goyon A, Zhang K. Goyon A, et al. Among authors: zhang k. Anal Chem. 2020 Apr 21;92(8):5944-5951. doi: 10.1021/acs.analchem.0c00114. Epub 2020 Mar 31. Anal Chem. 2020. PMID: 32191031

7

Characterization of High Molecular Weight Multi-Arm Functionalized PEG-Maleimide for Protein Conjugation by Charge-Reduction Mass Spectrometry Coupled to Two-Dimensional Liquid Chromatography.

Yang SH, Chen B, Wang J, Zhang K. Yang SH, et al. Among authors: zhang k. Anal Chem. 2020 Jun 16;92(12):8584-8590. doi: 10.1021/acs.analchem.0c01567. Epub 2020 Jun 7. Anal Chem. 2020. PMID: 32442374

8

Achiral-Chiral Two-Dimensional Liquid Chromatography Platform to Support Automated High-Throughput Experimentation in the Field of Drug Development.

Goyon A, Masui C, Sirois LE, Han C, Yehl P, Gosselin F, Zhang K. Goyon A, et al. Among authors: zhang k. Anal Chem. 2020 Nov 17;92(22):15187-15193. doi: 10.1021/acs.analchem.0c03754. Epub 2020 Nov 3. Anal Chem. 2020. PMID: 33142065

9

Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches.

Camperi J , Goyon A , Guillarme D , Zhang K , Stella C . Camperi J , et al. Among authors: zhang k. Analyst. 2021 Feb 7;146(3):747-769. doi: 10.1039/d0an01963a. Epub 2021 Jan 7. Analyst. 2021. PMID: 33410843 Review.

10

Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles.

Fan Y, Yen CW, Lin HC, Hou W, Estevez A, Sarode A, Goyon A, Bian J, Lin J, Koenig SG, Leung D, Nagapudi K, Zhang K. Fan Y, et al. Among authors: zhang k. Int J Pharm. 2021 Apr 15;599:120392. doi: 10.1016/j.ijpharm.2021.120392. Epub 2021 Feb 25. Int J Pharm. 2021. PMID: 33639228

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