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Dexmedetomidine directly binds to and inhibits Toll-like receptor 4.
Koutsogiannaki S, Limratana P, Bu W, Maisat W, McKinstry-Wu A, Han X, Ohto U, Eckenhoff RG, Soriano SG, Yuki K. Koutsogiannaki S, et al. Among authors: ohto u. Int Immunopharmacol. 2024 Nov 15;141:112975. doi: 10.1016/j.intimp.2024.112975. Epub 2024 Aug 19. Int Immunopharmacol. 2024. PMID: 39163686
Coagulation factor X activates innate immunity to human species C adenovirus.
Doronin K, Flatt JW, Di Paolo NC, Khare R, Kalyuzhniy O, Acchione M, Sumida JP, Ohto U, Shimizu T, Akashi-Takamura S, Miyake K, MacDonald JW, Bammler TK, Beyer RP, Farin FM, Stewart PL, Shayakhmetov DM. Doronin K, et al. Among authors: ohto u. Science. 2012 Nov 9;338(6108):795-8. doi: 10.1126/science.1226625. Epub 2012 Sep 27. Science. 2012. PMID: 23019612 Free PMC article.
Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.
Okuno T, Koutsogiannaki S, Hou L, Bu W, Ohto U, Eckenhoff RG, Yokomizo T, Yuki K. Okuno T, et al. Among authors: ohto u. FASEB J. 2019 Dec;33(12):14528-14541. doi: 10.1096/fj.201901570R. Epub 2019 Nov 2. FASEB J. 2019. PMID: 31675483 Free PMC article.
-Okuno, T., Koutsogiannaki, S., Hou, L., Bu, W., Ohto, U., Eckenhoff, R. G., Yokomizo, T., Yuki, K. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system....
-Okuno, T., Koutsogiannaki, S., Hou, L., Bu, W., Ohto, U., Eckenhoff, R. G., Yokomizo, T., Yuki, K. Volatile anesthetics isofl …
The effect of anesthetics on toll like receptor 9.
Koutsogiannaki S, Bu W, Hou L, Shibamura-Fujiogi M, Ishida H, Ohto U, Eckenhoff RG, Yuki K. Koutsogiannaki S, et al. Among authors: ohto u. FASEB J. 2020 Nov;34(11):14645-14654. doi: 10.1096/fj.202000791RR. Epub 2020 Sep 9. FASEB J. 2020. PMID: 32901993 Free PMC article.
Propofol directly binds to and inhibits TLR7.
Koutsogiannaki S, Bu W, Maisat W, Manzor M, Zhang Z, Ohto U, Eckenhoff RG, Yuki K. Koutsogiannaki S, et al. Among authors: ohto u. FASEB J. 2022 Aug;36(8):e22481. doi: 10.1096/fj.202200312R. FASEB J. 2022. PMID: 35899460 Free PMC article.
77 results