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Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis.
Irvine EB, Nikolov A, Khan MZ, Peters JM, Lu R, Sixsmith J, Wallace A, van Woudenbergh E, Shin S, Karpinski W, Hsiao JC, Casadevall A, Bryson BD, Cavacini L, Grace PS, Alter G, Fortune SM. Irvine EB, et al. Among authors: wallace a. Nat Microbiol. 2024 Sep;9(9):2369-2382. doi: 10.1038/s41564-024-01777-9. Epub 2024 Aug 22. Nat Microbiol. 2024. PMID: 39174703 Free PMC article.
Highly Specific Mouse Anti-Joining Chain of Human Immunoglobulin A.
Ejemel M, Gawron MA, Schneider MI, Wallace A, Schiller ZA, Schneider R, Martin Iii JC, Klempner MS, Wang Y, Cavacini LA. Ejemel M, et al. Among authors: wallace a. Monoclon Antib Immunodiagn Immunother. 2020 Dec;39(6):228-232. doi: 10.1089/mab.2020.0031. Epub 2020 Oct 29. Monoclon Antib Immunodiagn Immunother. 2020. PMID: 33121367
A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction.
Ejemel M, Li Q, Hou S, Schiller ZA, Tree JA, Wallace A, Amcheslavsky A, Kurt Yilmaz N, Buttigieg KR, Elmore MJ, Godwin K, Coombes N, Toomey JR, Schneider R, Ramchetty AS, Close BJ, Chen DY, Conway HL, Saeed M, Ganesa C, Carroll MW, Cavacini LA, Klempner MS, Schiffer CA, Wang Y. Ejemel M, et al. Among authors: wallace a. Nat Commun. 2020 Aug 21;11(1):4198. doi: 10.1038/s41467-020-18058-8. Nat Commun. 2020. PMID: 32826914 Free PMC article.
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.
Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, Dupuis AP, Payne AF, Maryam A, Yilmaz NK, McDonough KA, Pierce BG, Schiffer CA, Kruse AC, Klempner MS, Cavacini LA, Fitzgerald KA, Wang Y. Li Q, et al. Among authors: wallace a. Front Immunol. 2022 Sep 12;13:995412. doi: 10.3389/fimmu.2022.995412. eCollection 2022. Front Immunol. 2022. PMID: 36172366 Free PMC article.
Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design.
Amcheslavsky A, Wallace AL, Ejemel M, Li Q, McMahon CT, Stoppato M, Giuntini S, Schiller ZA, Pondish JR, Toomey JR, Schneider RM, Meisinger J, Heukers R, Kruse AC, Barry EM, Pierce BG, Klempner MS, Cavacini LA, Wang Y. Amcheslavsky A, et al. Among authors: wallace al. Sci Rep. 2021 Feb 2;11(1):2751. doi: 10.1038/s41598-021-81895-0. Sci Rep. 2021. PMID: 33531570 Free PMC article.
IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity.
Ejemel M, Li Q, Hou S, Schiller ZA, Wallace AL, Amcheslavsky A, Yilmaz NK, Toomey JR, Schneider R, Close BJ, Chen DY, Conway HL, Mohsan S, Cavacini LA, Klempner MS, Schiffer CA, Wang Y. Ejemel M, et al. Among authors: wallace al. bioRxiv [Preprint]. 2020 May 15:2020.05.15.096719. doi: 10.1101/2020.05.15.096719. bioRxiv. 2020. Update in: Nat Commun. 2020 Aug 21;11(1):4198. doi: 10.1038/s41467-020-18058-8 PMID: 32511396 Free PMC article. Updated. Preprint.
HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. Quitadamo B, et al. Among authors: wallace a. J Virol. 2018 Jan 2;92(2):e00841-17. doi: 10.1128/JVI.00841-17. Print 2018 Jan 15. J Virol. 2018. PMID: 29118121 Free PMC article.
2,258 results