Jäger MC - Search Results

1

Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids.

Jäger MC, González-Ruiz V, Joos FL, Winter DV, Boccard J, Degenhardt T, Brand S, Rudaz S, Thompson GR 3rd, Odermatt A. Jäger MC, et al. Front Pharmacol. 2024 Aug 8;15:1394846. doi: 10.3389/fphar.2024.1394846. eCollection 2024. Front Pharmacol. 2024. PMID: 39175536 Free PMC article.

2

Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis.

Patt M, Beck KR, Di Marco T, Jäger MC, González-Ruiz V, Boccard J, Rudaz S, Hartmann RW, Salah M, van Koppen CJ, Grill M, Odermatt A. Patt M, et al. Among authors: jager mc. Biochem Pharmacol. 2020 Feb;172:113781. doi: 10.1016/j.bcp.2019.113781. Epub 2019 Dec 27. Biochem Pharmacol. 2020. PMID: 31884045

3

Extended steroid profiling in H295R cells provides deeper insight into chemical-induced disturbances of steroidogenesis: Exemplified by prochloraz and anabolic steroids.

Jäger MC, Patt M, González-Ruiz V, Boccard J, Wey T, Winter DV, Rudaz S, Odermatt A. Jäger MC, et al. Mol Cell Endocrinol. 2023 Jun 15;570:111929. doi: 10.1016/j.mce.2023.111929. Epub 2023 Apr 8. Mol Cell Endocrinol. 2023. PMID: 37037411 Free article.

4

Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase.

Jäger MC, Kędzierski J, Gell V, Wey T, Kollár J, Winter DV, Schuster D, Smieško M, Odermatt A. Jäger MC, et al. Toxicol Appl Pharmacol. 2023 Sep 15;475:116638. doi: 10.1016/j.taap.2023.116638. Epub 2023 Jul 26. Toxicol Appl Pharmacol. 2023. PMID: 37499767 Free article.

5

Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays.

Jäger MC, Joos FL, Winter DV, Odermatt A. Jäger MC, et al. Curr Res Toxicol. 2023 Aug 14;5:100119. doi: 10.1016/j.crtox.2023.100119. eCollection 2023. Curr Res Toxicol. 2023. PMID: 37637492 Free PMC article.

6

In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1.

Kędzierski J, Jäger MC, Naeem S, Odermatt A, Smieško M. Kędzierski J, et al. Among authors: jager mc. Toxicol Appl Pharmacol. 2024 May;486:116945. doi: 10.1016/j.taap.2024.116945. Epub 2024 Apr 28. Toxicol Appl Pharmacol. 2024. PMID: 38688424 Free article.

7

Migraine inhibitor olcegepant reduces weight loss and IL-6 release in SARS-CoV-2-infected older mice with neurological signs.

Rahman SM, Buchholz DW, Imbiakha B, Jager MC, Leach J, Osborn RM, Birmingham AO, Dewhurst S, Aguilar HC, Luebke AE. Rahman SM, et al. Among authors: jager mc. J Virol. 2024 Jul 23;98(7):e0006624. doi: 10.1128/jvi.00066-24. Epub 2024 May 30. J Virol. 2024. PMID: 38814068 Free article.

8

Optic nerve meningioma and cloacal adenocarcinoma in a Humboldt penguin.

Nakagun S, Taylor RP, Houck EL, Eddy RM, Jager MC. Nakagun S, et al. Among authors: jager mc. J Vet Diagn Invest. 2024 Mar;36(2):238-242. doi: 10.1177/10406387231225651. Epub 2024 Jan 11. J Vet Diagn Invest. 2024. PMID: 38212884

9

Naturally acquired equine parvovirus-hepatitis is associated with a wide range of hepatic lesions in horses.

Jager MC, Choi E, Tomlinson JE, Van de Walle G. Jager MC, et al. Vet Pathol. 2024 May;61(3):442-452. doi: 10.1177/03009858231214024. Epub 2023 Nov 29. Vet Pathol. 2024. PMID: 38018088 Free PMC article.

10

Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5.

Imbiakha B, Ezzatpour S, Buchholz DW, Sahler J, Ye C, Olarte-Castillo XA, Zou A, Kwas C, O'Hare K, Choi A, Adeleke RA, Khomandiak S, Goodman L, Jager MC, Whittaker GR, Martinez-Sobrido L, August A, Aguilar HC. Imbiakha B, et al. Among authors: jager mc. Sci Adv. 2023 Sep 22;9(38):eadj1736. doi: 10.1126/sciadv.adj1736. Epub 2023 Sep 22. Sci Adv. 2023. PMID: 37738347 Free PMC article.

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