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133 results

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Page 1
The VLA-4 integrin is constitutively active in circulating chronic lymphocytic leukemia cells via BCR autonomous signaling: a novel anchor-independent mechanism exploiting soluble blood-borne ligands.
Tissino E, Gaglio A, Nicolò A, Pozzo F, Bittolo T, Rossi FM, Bomben R, Nanni P, Cattarossi I, Zaina E, Zimbo AM, Ianna G, Capasso G, Forestieri G, Moia R, Datta M, Härzschel A, Olivieri J, D'Arena G, Laurenti L, Zaja F, Chiarenza A, Palumbo GA, Martino EA, Gentile M, Rossi D, Gaidano G, Del Poeta G, Laureana R, Del Principe MI, Maity PC, Jumaa H, Hartmann TN, Zucchetto A, Gattei V. Tissino E, et al. Among authors: jumaa h. Leukemia. 2024 Oct;38(10):2127-2140. doi: 10.1038/s41375-024-02376-7. Epub 2024 Aug 14. Leukemia. 2024. PMID: 39143370 Free PMC article.
Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability.
Harms M, Haase A, Rodríguez-Alfonso A, Löffler J, Almeida-Hernández Y, Ruiz-Blanco YB, Albers D, Gilg A, von Bank F, Zech F, Groß R, Datta M, Jaikishan J, Draphoen B, Habib M, Ständker L, Wiese S, Lindén M, Winter G, Rasche V, Beer AJ, Jumaa H, Abadi AH, Kirchhoff F, Busch M, Dünker N, Sanchez-Garcia E, Münch J. Harms M, et al. Among authors: jumaa h. J Control Release. 2024 Sep;373:583-598. doi: 10.1016/j.jconrel.2024.07.049. Epub 2024 Jul 30. J Control Release. 2024. PMID: 39047872 Free article.
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL.
Eken JA, Koning MT, Kupcova K, Sepúlveda Yáñez JH, de Groen RAL, Quinten E, Janssen J, van Bergen CAM, Vermaat JSP, Cleven A, Navarrete MA, Ylstra B, de Jong D, Havranek O, Jumaa H, Veelken H. Eken JA, et al. Among authors: jumaa h. J Exp Med. 2024 May 6;221(5):e20230941. doi: 10.1084/jem.20230941. Epub 2024 Mar 21. J Exp Med. 2024. PMID: 38512136 Free PMC article.
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia.
Quinten E, Sepúlveda-Yáñez JH, Koning MT, Eken JA, Pfeifer D, Nteleah V, De Groen RAL, Saravia DA, Knijnenburg J, Stuivenberg-Bleijswijk HE, Pantic M, Agathangelidis A, Keppler-Hafkemeyer A, Van Bergen CAM, Uribe-Paredes R, Stamatopoulos K, Vermaat JSP, Zirlik K, Navarrete MA, Jumaa H, Veelken H. Quinten E, et al. Among authors: jumaa h. Haematologica. 2024 Mar 1;109(3):824-834. doi: 10.3324/haematol.2022.282542. Haematologica. 2024. PMID: 37439337 Free PMC article.
Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.
Cosgun KN, Jumaa H, Robinson ME, Kistner KM, Xu L, Xiao G, Chan LN, Lee J, Kume K, Leveille E, Fonseca-Arce D, Khanduja D, Ng HL, Feldhahn N, Song J, Chan WC, Chen J, Taketo MM, Kothari S, Davids MS, Schjerven H, Jellusova J, Müschen M. Cosgun KN, et al. Among authors: jumaa h. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532152. doi: 10.1101/2023.03.13.532152. bioRxiv. 2023. PMID: 36993619 Free PMC article. Preprint.
Rheumatoid factor IgM autoantibodies control IgG homeostasis.
Nicolò A, Amendt T, El Ayoubi O, Young M, Finzel S, Senel M, Voll RE, Jumaa H. Nicolò A, et al. Among authors: jumaa h. Front Immunol. 2022 Oct 21;13:1016263. doi: 10.3389/fimmu.2022.1016263. eCollection 2022. Front Immunol. 2022. PMID: 36341420 Free PMC article.
Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia.
Lenk L, Winterberg D, Vogiatzi F, Laqua A, Spory L, Mayar A, Dietterle A, Münch G, Vokuhl C, Richter J, Polson AG, Schüler T, Kahlert UD, Peipp M, Valerius T, Schrappe M, Cario G, Jumaa H, Hobeika E, Brüggemann M, Alsadeq A, Schewe DM. Lenk L, et al. Among authors: jumaa h. Hemasphere. 2022 Jul 15;6(8):e754. doi: 10.1097/HS9.0000000000000754. eCollection 2022 Aug. Hemasphere. 2022. PMID: 35935606 Free PMC article. No abstract available.
133 results