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Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle.
McNamara JW, Parker BL, Voges HK, Mehdiabadi NR, Bolk F, Ahmad F, Chung JD, Charitakis N, Molendijk J, Zech ATL, Lal S, Ramialison M, Karavendzas K, Pointer HL, Syrris P, Lopes LR, Elliott PM, Lynch GS, Mills RJ, Hudson JE, Watt KI, Porrello ER, Elliott DA. McNamara JW, et al. Among authors: parker bl. Nat Cardiovasc Res. 2023 Feb;2(2):159-173. doi: 10.1038/s44161-023-00219-9. Epub 2023 Feb 15. Nat Cardiovasc Res. 2023. PMID: 39196058 Free PMC article.
Vascular cells improve functionality of human cardiac organoids.
Voges HK, Foster SR, Reynolds L, Parker BL, Devilée L, Quaife-Ryan GA, Fortuna PRJ, Mathieson E, Fitzsimmons R, Lor M, Batho C, Reid J, Pocock M, Friedman CE, Mizikovsky D, Francois M, Palpant NJ, Needham EJ, Peralta M, Monte-Nieto GD, Jones LK, Smyth IM, Mehdiabadi NR, Bolk F, Janbandhu V, Yao E, Harvey RP, Chong JJH, Elliott DA, Stanley EG, Wiszniak S, Schwarz Q, James DE, Mills RJ, Porrello ER, Hudson JE. Voges HK, et al. Among authors: parker bl. Cell Rep. 2023 May 30;42(5):112322. doi: 10.1016/j.celrep.2023.112322. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37105170 Free article.
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.
Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: parker bl. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15. Proc Natl Acad Sci U S A. 2017. PMID: 28916735 Free PMC article.
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.
Mills RJ, Parker BL, Quaife-Ryan GA, Voges HK, Needham EJ, Bornot A, Ding M, Andersson H, Polla M, Elliott DA, Drowley L, Clausen M, Plowright AT, Barrett IP, Wang QD, James DE, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: parker bl. Cell Stem Cell. 2019 Jun 6;24(6):895-907.e6. doi: 10.1016/j.stem.2019.03.009. Epub 2019 Mar 28. Cell Stem Cell. 2019. PMID: 30930147 Free article.
urPTMdb/TeaProt: Upstream and Downstream Proteomics Analysis.
Molendijk J, Yip R, Parker BL. Molendijk J, et al. Among authors: parker bl. J Proteome Res. 2023 Feb 3;22(2):302-310. doi: 10.1021/acs.jproteome.2c00048. Epub 2022 Jun 27. J Proteome Res. 2023. PMID: 35759515 Free PMC article.
Development of a human skeletal micro muscle platform with pacing capabilities.
Mills RJ, Parker BL, Monnot P, Needham EJ, Vivien CJ, Ferguson C, Parton RG, James DE, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: parker bl. Biomaterials. 2019 Apr;198:217-227. doi: 10.1016/j.biomaterials.2018.11.030. Epub 2018 Nov 28. Biomaterials. 2019. PMID: 30527761
Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function.
Blazev R, Carl CS, Ng YK, Molendijk J, Voldstedlund CT, Zhao Y, Xiao D, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Blazev R, et al. Among authors: parker bl. Cell Metab. 2022 Oct 4;34(10):1561-1577.e9. doi: 10.1016/j.cmet.2022.07.003. Epub 2022 Jul 25. Cell Metab. 2022. PMID: 35882232 Free article.
216 results