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Page 1
Age-dependent sex differences in cardiometabolic risk factors.
Zhernakova DV, Sinha T, Andreu-Sánchez S, Prins JR, Kurilshikov A, Balder JW, Sanna S; Lifelines Cohort Study; Franke L, Kuivenhoven JA, Zhernakova A, Fu J. Zhernakova DV, et al. Among authors: kuivenhoven ja. Nat Cardiovasc Res. 2022 Sep;1(9):844-854. doi: 10.1038/s44161-022-00131-8. Epub 2022 Sep 12. Nat Cardiovasc Res. 2022. PMID: 39196077 Free PMC article.
Genome-wide Studies Reveal Genetic Risk Factors for Hepatic Fat Content.
Li Y, van den Berg EH, Kurilshikov A, Zhernakova DV, Gacesa R, Hu S, Lopera-Maya EA, Zhernakova A; Lifelines Cohort Study; de Meijer VE, Sanna S, Dullaart RPF, Blokzijl H, Festen EAM, Fu J, Weersma RK. Li Y, et al. Genomics Proteomics Bioinformatics. 2024 Jul 3;22(2):qzae031. doi: 10.1093/gpbjnl/qzae031. Genomics Proteomics Bioinformatics. 2024. PMID: 39142818
Phenotypic and Genetic Factors Associated with Absence of Cardiomyopathy Symptoms in PLN:c.40_42delAGA Carriers.
Lopera-Maya EA, Li S, de Brouwer R, Nolte IM, van Breen J; Netherlands A. C. M./P. L. N. Registry; Lifelines Cohort Study; Jongbloed JDH, Swertz MA, Snieder H, Franke L, Wijmenga C, de Boer RA, Deelen P, van der Zwaag PA, Sanna S. Lopera-Maya EA, et al. J Cardiovasc Transl Res. 2023 Dec;16(6):1251-1266. doi: 10.1007/s12265-022-10347-5. Epub 2023 Jan 9. J Cardiovasc Transl Res. 2023. PMID: 36622581 Free PMC article.
Host genetic regulation of human gut microbial structural variation.
Zhernakova DV, Wang D, Liu L, Andreu-Sánchez S, Zhang Y, Ruiz-Moreno AJ, Peng H, Plomp N, Del Castillo-Izquierdo Á, Gacesa R, Lopera-Maya EA, Temba GS, Kullaya VI, van Leeuwen SS; Lifelines Cohort Study; Xavier RJ, de Mast Q, Joosten LAB, Riksen NP, Rutten JHW, Netea MG, Sanna S, Wijmenga C, Weersma RK, Zhernakova A, Harmsen HJM, Fu J. Zhernakova DV, et al. Nature. 2024 Jan;625(7996):813-821. doi: 10.1038/s41586-023-06893-w. Epub 2024 Jan 3. Nature. 2024. PMID: 38172637 Free PMC article.
Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries.
Zheng Z, Liu S, Sidorenko J, Wang Y, Lin T, Yengo L, Turley P, Ani A, Wang R, Nolte IM, Snieder H; LifeLines Cohort Study; Yang J, Wray NR, Goddard ME, Visscher PM, Zeng J. Zheng Z, et al. Nat Genet. 2024 May;56(5):767-777. doi: 10.1038/s41588-024-01704-y. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689000 Free PMC article.
Multi-ancestry polygenic risk scores for venous thromboembolism.
Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët DA, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H; Lifelines Cohort Study; Kabrhel C, Smith NL, Kraft P; INVENT Consortium. Jee YH, et al. Hum Mol Genet. 2024 Sep 3;33(18):1584-1591. doi: 10.1093/hmg/ddae097. Hum Mol Genet. 2024. PMID: 38879759
A suite of genome-engineered hepatic cells provides novel insights into the spatiotemporal metabolism of apolipoprotein B and apolipoprotein B-containing lipoprotein secretion.
Meurs A, Ndoj K, van den Berg M, Marinković G, Tantucci M, Veenendaal T, Kuivenhoven JA, Klumperman J, Zelcer N. Meurs A, et al. Among authors: kuivenhoven ja. Cardiovasc Res. 2024 Sep 21;120(11):1253-1264. doi: 10.1093/cvr/cvae121. Cardiovasc Res. 2024. PMID: 38833612 Free PMC article.
Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.
Heida A, van Dijk T, Smit M, Koehorst M, Koster M, Kloosterhuis N, Havinga R, Bloks VW, Wolters JC, de Bruin A, Kuivenhoven JA, de Boer JF, Kuipers F, van de Sluis B. Heida A, et al. Among authors: kuivenhoven ja. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Mar;1869(2):159445. doi: 10.1016/j.bbalip.2023.159445. Epub 2023 Dec 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2024. PMID: 38086439 Free article.
ERICH4 is not involved in the assembly and secretion of intestinal lipoproteins.
Visser A, van Zwol W, Kloosterhuis N, Huijkman N, Smit M, Koster M, Bloks V, Hussain MM, van de Sluis B, Kuivenhoven JA. Visser A, et al. Among authors: kuivenhoven ja. Atherosclerosis. 2024 Oct 18;399:118635. doi: 10.1016/j.atherosclerosis.2024.118635. Online ahead of print. Atherosclerosis. 2024. PMID: 39492093 Free article.
189 results