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Impaired cell fate through gain-of-function mutations in a chromatin reader.
Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll TS, Li Y, Feng L, Chen G, Wang SP, Ortiz MV, Daley SK, Wang X, Xuan H, Kentsis A, Muir TW, Roeder RG, Li H, Li W, Tjian R, Wen H, Allis CD. Wan L, et al. Among authors: xuan f, xuan h. Nature. 2020 Jan;577(7788):121-126. doi: 10.1038/s41586-019-1842-7. Epub 2019 Dec 18. Nature. 2020. PMID: 31853060 Free PMC article.
Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Tencer AH, Yu Y, Causse SZ, Campbell GR, Klein BJ, Xuan H, Cartier J, Miles MA, Gaurav N, Zadoroznyj A, Holt TA, Wen H, Hawkins CJ, Spector SA, Dubrez L, Shi X, Kutateladze TG. Tencer AH, et al. Among authors: xuan h. Nat Struct Mol Biol. 2023 Sep;30(9):1265-1274. doi: 10.1038/s41594-023-01044-1. Epub 2023 Jul 31. Nat Struct Mol Biol. 2023. PMID: 37524969 Free PMC article.
TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis.
Liu H, Liu Y, Jin SG, Johnson J, Xuan H, Lu D, Li J, Zhai L, Li X, Zhao Y, Liu M, Craig SEL, Floramo JS, Molchanov V, Li J, Li JD, Krawczyk C, Shi X, Pfeifer GP, Yang T. Liu H, et al. Among authors: xuan h. Cell Rep. 2023 Jan 31;42(1):112012. doi: 10.1016/j.celrep.2023.112012. Epub 2023 Jan 20. Cell Rep. 2023. PMID: 36680774 Free PMC article.
343 results