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Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse.
Kats I, Simovic-Lorenz M, Schreiber HS, Sant P, Mallm JP, Körber V, Li A, Velmurugan P, Heuer S, Kües L, Devens F, Sill M, Jugold M, Moustafa M, Abdollahi A, Winkler F, Korshunov A, Pfister SM, Stegle O, Ernst A. Kats I, et al. Among authors: ernst a. Nat Commun. 2024 Nov 29;15(1):10370. doi: 10.1038/s41467-024-54709-w. Nat Commun. 2024. PMID: 39609432
Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Smirnov P, Przybilla MJ, Simovic-Lorenz M, Parra RG, Susak H, Ratnaparkhe M, Wong JK, Körber V, Mallm JP, Philippos G, Sill M, Kolb T, Kumar R, Casiraghi N, Okonechnikov K, Ghasemi DR, Maaß KK, Pajtler KW, Jauch A, Korshunov A, Höfer T, Zapatka M, Pfister SM, Huber W, Stegle O, Ernst A. Smirnov P, et al. Among authors: ernst a. Nat Commun. 2024 Nov 23;15(1):10183. doi: 10.1038/s41467-024-54547-w. Nat Commun. 2024. PMID: 39580568 Free PMC article.
Exploitation of the fibrinolytic system by B-cell acute lymphoblastic leukemia and its therapeutic targeting.
Minciacchi VR, Bravo J, Karantanou C, Pereira RS, Zanetti C, Kumar R, Thomasberger N, Llavona P, Krack T, Bankov K, Meister M, Hartmann S, Maguer-Satta V, Lefort S, Putyrski M, Ernst A, Huntly BJP, Meduri E, Ruf W, Krause DS. Minciacchi VR, et al. Among authors: ernst a. Nat Commun. 2024 Nov 20;15(1):10059. doi: 10.1038/s41467-024-54361-4. Nat Commun. 2024. PMID: 39567540 Free PMC article.
Chromothripsis in cancer.
Simovic-Lorenz M, Ernst A. Simovic-Lorenz M, et al. Among authors: ernst a. Nat Rev Cancer. 2024 Nov 15. doi: 10.1038/s41568-024-00769-5. Online ahead of print. Nat Rev Cancer. 2024. PMID: 39548283 Review.
Double exchange interaction in Mn-based topological kagome ferrimagnet.
Wang J, Ernst A, Antonov VN, Jiang Q, Qian H, Wang D, Cao J, Zhu F, Qiao S, Ye M. Wang J, et al. Among authors: ernst a. Commun Phys. 2024;7(1):350. doi: 10.1038/s42005-024-01838-9. Epub 2024 Oct 26. Commun Phys. 2024. PMID: 39469528 Free PMC article.
TERT Expression and Clinical Outcome in Pulmonary Carcinoids.
Werr L, Bartenhagen C, Rosswog C, Cartolano M, Voegele C, Sexton-Oates A, Di Genova A, Ernst A, Kahlert Y, Hemstedt N, Höppner S, Mansuet Lupo A, Pelosi G, Brcic L, Papotti M, George J, Bosco G, Quaas A, Tang LH, Robzyk K, Kadota K, Roh MS, Fanaroff RE, Falcon CJ, Büttner R, Lantuejoul S, Rekhtman N, Rudin CM, Travis WD, Alcala N, Fernandez-Cuesta L, Foll M, Peifer M, Thomas RK, Fischer M; Lung NEN Network. Werr L, et al. Among authors: ernst a. J Clin Oncol. 2024 Sep 30:JCO2302708. doi: 10.1200/JCO.23.02708. Online ahead of print. J Clin Oncol. 2024. PMID: 39348606
1,267 results