Bolshakov VY - Search Results

1

An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function.

Kambali M, Li Y, Unichenko P, Feria Pliego JA, Yadav R, Liu J, McGuinness P, Cobb JG, Wang M, Nagarajan R, Lyu J, Vongsouthi V, Jackson CJ, Engin E, Coyle JT, Shin J, Hodgson NW, Hensch TK, Talkowski ME, Homanics GE, Bolshakov VY, Henneberger C, Rudolph U. Kambali M, et al. Among authors: bolshakov vy. Mol Psychiatry. 2024 Aug 30. doi: 10.1038/s41380-024-02711-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39210012

2

Cell selective conditional null mutations of serine racemase demonstrate a predominate localization in cortical glutamatergic neurons.

Benneyworth MA, Li Y, Basu AC, Bolshakov VY, Coyle JT. Benneyworth MA, et al. Among authors: bolshakov vy. Cell Mol Neurobiol. 2012 May;32(4):613-24. doi: 10.1007/s10571-012-9808-4. Epub 2012 Feb 24. Cell Mol Neurobiol. 2012. PMID: 22362148 Free PMC article.

3

Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level.

Li Y, Sacchi S, Pollegioni L, Basu AC, Coyle JT, Bolshakov VY. Li Y, et al. Among authors: bolshakov vy. Nat Commun. 2013;4:1760. doi: 10.1038/ncomms2779. Nat Commun. 2013. PMID: 23612301 Free PMC article.

4

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction.

Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT. Balu DT, et al. Among authors: bolshakov vy. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2400-9. doi: 10.1073/pnas.1304308110. Epub 2013 May 31. Proc Natl Acad Sci U S A. 2013. PMID: 23729812 Free PMC article.

5

Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.

Li Y, Krupa B, Kang JS, Bolshakov VY, Liu G. Li Y, et al. Among authors: bolshakov vy. J Neurophysiol. 2009 Jul;102(1):578-89. doi: 10.1152/jn.91342.2008. Epub 2009 May 13. J Neurophysiol. 2009. PMID: 19439669 Free PMC article.

6

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference.

Engin E, Zarnowska ED, Benke D, Tsvetkov E, Sigal M, Keist R, Bolshakov VY, Pearce RA, Rudolph U. Engin E, et al. Among authors: bolshakov vy. J Neurosci. 2015 Oct 7;35(40):13698-712. doi: 10.1523/JNEUROSCI.1370-15.2015. J Neurosci. 2015. PMID: 26446222 Free PMC article.

7

An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.

Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT. Balu DT, et al. Among authors: bolshakov vy. Neuropsychopharmacology. 2016 Jul;41(8):2052-61. doi: 10.1038/npp.2016.2. Epub 2016 Jan 7. Neuropsychopharmacology. 2016. PMID: 26741285 Free PMC article.

8

Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.

Riccio A, Li Y, Tsvetkov E, Gapon S, Yao GL, Smith KS, Engin E, Rudolph U, Bolshakov VY, Clapham DE. Riccio A, et al. Among authors: bolshakov vy. J Neurosci. 2014 Mar 5;34(10):3653-67. doi: 10.1523/JNEUROSCI.2274-13.2014. J Neurosci. 2014. PMID: 24599464 Free PMC article.

9

Modulation of anxiety and fear via distinct intrahippocampal circuits.

Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy JM, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Engin E, et al. Among authors: bolshakov vy. Elife. 2016 Mar 14;5:e14120. doi: 10.7554/eLife.14120. Elife. 2016. PMID: 26971710 Free PMC article.

10

Keeping in check painful synapses in central amygdala.

Tully K, Li Y, Bolshakov VY. Tully K, et al. Among authors: bolshakov vy. Neuron. 2007 Dec 6;56(5):757-9. doi: 10.1016/j.neuron.2007.11.011. Neuron. 2007. PMID: 18054852 Free article.

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