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The Australasian Registry for Severe Cutaneous Adverse Reactions (AUS-SCAR) - Providing a roadmap for closing the diagnostic, patient, and healthcare gaps for a group of rare drug eruptions.
James F, Goh MS, Vogrin S, Ng I, Douglas AP, Holmes NE, Chua KY, De Luca J, Sharma P, Zubrinich C, Aung AK, Gin D, Lambros B, Baker C, Foley P, Chong AH, Thien F, Fok JS, Su J, Scardamaglia L, Awad A, Tong S, Johnson D, Godsell J, Arasu A, Barnes S, Ojaimi S, Mar A, Yun J, Ange N, Tong WWY, Carr A, Loprete J, Katelaris CH, Slape D, Keat K, West TA, Lee M, Smith W, Hissaria P, Sidhu S, Janson S, Venkatesan S, Davies J, Lane MJ, Redmond AM, Robertson I, Legg A, Fernando S, Boyle T, Li J, Phillips EJ, Cleland H, Kern JS, Trubiano JA. James F, et al. Among authors: ng i. World Allergy Organ J. 2024 Aug 5;17(8):100936. doi: 10.1016/j.waojou.2024.100936. eCollection 2024 Aug. World Allergy Organ J. 2024. PMID: 39211425 Free PMC article.
Intestinal-specific Hdac3 deletion increases susceptibility to colitis and small intestinal tumor development in mice fed a high-fat diet.
Ng I, Luk IY, Nightingale R, Reehorst CM, Dávalos-Salas M, Jenkins LJ, Fong C, Williams DS, Watt MJ, Dhillon AS, Mariadason JM. Ng I, et al. Am J Physiol Gastrointest Liver Physiol. 2023 Dec 1;325(6):G508-G517. doi: 10.1152/ajpgi.00160.2023. Epub 2023 Oct 3. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37788331
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death.
Jenkins LJ, Luk IY, Fairlie WD, Lee EF, Palmieri M, Schoffer KL, Tan T, Ng I, Vukelic N, Tran S, Tse JWT, Nightingale R, Alam Z, Chionh F, Iatropoulos G, Ernst M, Afshar-Sterle S, Desai J, Gibbs P, Sieber OM, Dhillon AS, Tebbutt NC, Mariadason JM. Jenkins LJ, et al. Among authors: ng i. Mol Cancer Ther. 2023 Jan 3;22(1):52-62. doi: 10.1158/1535-7163.MCT-22-0101. Mol Cancer Ther. 2023. PMID: 36343387 Free PMC article.
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Dávalos-Salas M, Montgomery MK, Reehorst CM, Nightingale R, Ng I, Anderton H, Al-Obaidi S, Lesmana A, Scott CM, Ioannidis P, Kalra H, Keerthikumar S, Tögel L, Rigopoulos A, Gong SJ, Williams DS, Yoganantharaja P, Bell-Anderson K, Mathivanan S, Gibert Y, Hiebert S, Scott AM, Watt MJ, Mariadason JM. Dávalos-Salas M, et al. Among authors: ng i. Nat Commun. 2019 Nov 22;10(1):5291. doi: 10.1038/s41467-019-13180-8. Nat Commun. 2019. PMID: 31757939 Free PMC article.
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression.
Luk IY, Jenkins LJ, Schoffer KL, Ng I, Tse JWT, Mouradov D, Kaczmarczyk S, Nightingale R, Burrows AD, Anderson RL, Arango D, Dopeso H, Croft L, Richardson MF, Sieber OM, Liao Y, Mooi JK, Vukelic N, Reehorst CM, Afshar-Sterle S, Whitehall VLJ, Fennell L, Abud HE, Tebbutt NC, Phillips WA, Williams DS, Shi W, Mielke LA, Ernst M, Dhillon AS, Clemons NJ, Mariadason JM. Luk IY, et al. Among authors: ng i. Cell Death Differ. 2022 Nov;29(11):2288-2302. doi: 10.1038/s41418-022-01016-w. Epub 2022 May 23. Cell Death Differ. 2022. PMID: 35606410 Free PMC article.
1,008 results