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Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, Nandi A, Anderson S, Han N, Manne S, Kiner E, Sachar C, Lucas M, George S, Yan PK, Kier MW, Laughlin AI, Kothari S, Giles J, Mathew D, Ghinnagow R, Alanio C, Flowers A, Xu W, Tenney DJ, Xu X, Amaravadi RK, Karakousis GC, Schuchter LM, Buggert M, Oldridge D, Minn AJ, Blank C, Weber JS, Mitchell TC, Farwell MD, Herati RS, Huang AC. Wang K, et al. Among authors: herati rs. Cancer Cell. 2024 Sep 9;42(9):1582-1597.e10. doi: 10.1016/j.ccell.2024.08.007. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214097
SARS-CoV-2 inflammation durably imprints memory CD4 T cells.
Gray-Gaillard SL, Solis SM, Chen HM, Monteiro C, Ciabattoni G, Samanovic MI, Cornelius AR, Williams T, Geesey E, Rodriguez M, Ortigoza MB, Ivanova EN, Koralov SB, Mulligan MJ, Herati RS. Gray-Gaillard SL, et al. Among authors: herati rs. Sci Immunol. 2024 Jun 21;9(96):eadj8526. doi: 10.1126/sciimmunol.adj8526. Epub 2024 Jun 21. Sci Immunol. 2024. PMID: 38905326
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, Zhang W, Dowdell AK, Kim JI, Andrijevic D, Khalil K, Jaffe IS, Loza BL, Gragert L, Camellato BR, Oliveira MF, O'Brien DP, Chen HM, Weldon E, Gao H, Gandla D, Chang A, Bhatt R, Gao S, Lin X, Reddy KP, Kagermazova L, Habara AH, Widawsky S, Liang FX, Sall J, Loupy A, Heguy A, Taylor SEB, Zhu Y, Michael B, Jiang L, Jian R, Chong AS, Fairchild RL, Linna-Kuosmanen S, Kaikkonen MU, Tatapudi V, Lorber M, Ayares D, Mangiola M, Narula N, Moazami N, Pass H, Herati RS, Griesemer A, Kellis M, Snyder MP, Montgomery RA, Boeke JD, Keating BJ. Schmauch E, et al. Among authors: herati rs. Nat Med. 2024 May;30(5):1448-1460. doi: 10.1038/s41591-024-02972-1. Epub 2024 May 17. Nat Med. 2024. PMID: 38760586
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection.
Ivanova EN, Shwetar J, Devlin JC, Buus TB, Gray-Gaillard S, Koide A, Cornelius A, Samanovic MI, Herrera A, Mimitou EP, Zhang C, Karmacharya T, Desvignes L, Ødum N, Smibert P, Ulrich RJ, Mulligan MJ, Koide S, Ruggles KV, Herati RS, Koralov SB. Ivanova EN, et al. Among authors: herati rs. iScience. 2023 Nov 24;26(12):108572. doi: 10.1016/j.isci.2023.108572. eCollection 2023 Dec 15. iScience. 2023. PMID: 38213787 Free PMC article.
Immune response, phenotyping and molecular graft surveillance in kidney transplant recipients following severe acute respiratory syndrome coronavirus 2 vaccination.
Ali NM, Herati RS, Mehta SA, Leonard J, Miles J, Lonze BE, DiMaggio C, Tatapudi VS, Stewart ZA, Alnazari N, Neumann HJ, Thomas J, Cartiera K, Weldon E, Michael J, Hickson C, Whiteson H, Khalil K, Stern JM, Allen JR, Tuen M, Gray-Gaillard SL, Solis SM, Samanovic MI, Mulligan MJ, Montgomery RA. Ali NM, et al. Among authors: herati rs. Transpl Infect Dis. 2023 Dec;25(6):e14122. doi: 10.1111/tid.14122. Epub 2023 Sep 14. Transpl Infect Dis. 2023. PMID: 37707287
Human T follicular helper clones seed the germinal center-resident regulatory pool.
Le Coz C, Oldridge DA, Herati RS, De Luna N, Garifallou J, Cruz Cabrera E, Belman JP, Pueschl D, Silva LV, Knox AVC, Reid W, Yoon S, Zur KB, Handler SD, Hakonarson H, Wherry EJ, Gonzalez M, Romberg N. Le Coz C, et al. Among authors: herati rs. Sci Immunol. 2023 Apr 14;8(82):eade8162. doi: 10.1126/sciimmunol.ade8162. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027481 Free PMC article.
Multimodal characterization of antigen-specific CD8 + T cells across SARS-CoV-2 vaccination and infection.
Zhang B, Upadhyay R, Hao Y, Samanovic MI, Herati RS, Blair J, Axelrad J, Mulligan MJ, Littman DR, Satija R. Zhang B, et al. Among authors: herati rs. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525203. doi: 10.1101/2023.01.24.525203. bioRxiv. 2023. Update in: Nat Immunol. 2023 Oct;24(10):1725-1734. doi: 10.1038/s41590-023-01608-9 PMID: 36747786 Free PMC article. Updated. Preprint.
47 results