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Page 1
Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts.
Uhrbom M, Muhl L, Genové G, Liu J, Palmgren H, Alexandersson I, Karlsson F, Zhou AX, Lunnerdal S, Gustafsson S, Buyandelger B, Petkevicius K, Ahlstedt I, Karlsson D, Aasehaug L, He L, Jeansson M, Betsholtz C, Peng XR. Uhrbom M, et al. Among authors: karlsson d. Nat Commun. 2024 Sep 2;15(1):7643. doi: 10.1038/s41467-024-51867-9. Nat Commun. 2024. PMID: 39223126 Free PMC article.
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.
Petkevicius K, Palmgren H, Glover MS, Ahnmark A, Andréasson AC, Madeyski-Bengtson K, Kawana H, Allman EL, Kaper D, Uhrbom M, Andersson L, Aasehaug L, Forsström J, Wallin S, Ahlstedt I, Leke R, Karlsson D, González-King H, Löfgren L, Nilsson R, Pellegrini G, Kono N, Aoki J, Hess S, Sienski G, Pilon M, Bohlooly-Y M, Maresca M, Peng XR. Petkevicius K, et al. Among authors: karlsson d. Nat Commun. 2022 Oct 14;13(1):6020. doi: 10.1038/s41467-022-33735-6. Nat Commun. 2022. PMID: 36241646 Free PMC article.
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.
Palmgren H, Petkevicius K, Bartesaghi S, Ahnmark A, Ruiz M, Nilsson R, Löfgren L, Glover MS, Andréasson AC, Andersson L, Becquart C, Kurczy M, Kull B, Wallin S, Karlsson D, Hess S, Maresca M, Bohlooly-Y M, Peng XR, Pilon M. Palmgren H, et al. Among authors: karlsson d. Diabetes. 2023 Oct 1;72(10):1350-1363. doi: 10.2337/db22-0293. Diabetes. 2023. PMID: 36580483 Free PMC article.
Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.
Hansson SF, Zhou AX, Vachet P, Eriksson JW, Pereira MJ, Skrtic S, Jongsma Wallin H, Ericsson-Dahlstrand A, Karlsson D, Ahnmark A, Sörhede Winzell M, Magnone MC, Davidsson P. Hansson SF, et al. Among authors: karlsson d. PLoS One. 2018 Apr 27;13(4):e0196601. doi: 10.1371/journal.pone.0196601. eCollection 2018. PLoS One. 2018. PMID: 29702679 Free PMC article.
Intestinal sodium/glucose cotransporter 3 expression is epithelial and downregulated in obesity.
Soták M, Casselbrant A, Rath E, Zietek T, Strömstedt M, Adingupu DD, Karlsson D, Fritsch Fredin M, Ergang P, Pácha J, Batorsky A, Alpers CE, Börgeson E, Hansen PBL, Ericsson A, Björnson Granqvist A, Wallenius V, Fändriks L, Unwin RJ. Soták M, et al. Among authors: karlsson d. Life Sci. 2021 Feb 15;267:118974. doi: 10.1016/j.lfs.2020.118974. Epub 2020 Dec 30. Life Sci. 2021. PMID: 33385407 Free article.
Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation.
O'Mahony G, Petersen J, Ek M, Rae R, Johansson C, Jianming L, Prokoph N, Bergström F, Bamberg K, Giordanetto F, Zarrouki B, Karlsson D, Hogner A. O'Mahony G, et al. Among authors: karlsson d. ACS Med Chem Lett. 2022 Mar 11;13(4):681-686. doi: 10.1021/acsmedchemlett.1c00715. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450368 Free PMC article.
Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability.
King AJ, Siegel M, He Y, Nie B, Wang J, Koo-McCoy S, Minassian NA, Jafri Q, Pan D, Kohler J, Kumaraswamy P, Kozuka K, Lewis JG, Dragoli D, Rosenbaum DP, O'Neill D, Plain A, Greasley PJ, Jönsson-Rylander AC, Karlsson D, Behrendt M, Strömstedt M, Ryden-Bergsten T, Knöpfel T, Pastor Arroyo EM, Hernando N, Marks J, Donowitz M, Wagner CA, Alexander RT, Caldwell JS. King AJ, et al. Among authors: karlsson d. Sci Transl Med. 2018 Aug 29;10(456):eaam6474. doi: 10.1126/scitranslmed.aam6474. Sci Transl Med. 2018. PMID: 30158152 Free PMC article. Clinical Trial.
Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction.
Yndigegn T, Lindahl B, Mars K, Alfredsson J, Benatar J, Brandin L, Erlinge D, Hallen O, Held C, Hjalmarsson P, Johansson P, Karlström P, Kellerth T, Marandi T, Ravn-Fischer A, Sundström J, Östlund O, Hofmann R, Jernberg T; REDUCE-AMI Investigators. Yndigegn T, et al. N Engl J Med. 2024 Apr 18;390(15):1372-1381. doi: 10.1056/NEJMoa2401479. Epub 2024 Apr 7. N Engl J Med. 2024. PMID: 38587241 Clinical Trial.
149 results