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An atlas of genetic effects on cellular composition of the tumor microenvironment.
Cai Y, Lu Z, Chen C, Zhu Y, Chen Z, Wu Z, Peng J, Zhu X, Liu Z, Li B, Zhang M, Huang J, Li Y, Liu Y, Ma Q, He C, Chen S, Tian W, Fan L, Ning C, Geng H, Xu B, Li H, Zhu X, Fang J, Wang X, Zhang S, Jin M, Huang C, Yang X, Tian J, Miao X. Cai Y, et al. Among authors: li y, li h, li b. Nat Immunol. 2024 Oct;25(10):1959-1975. doi: 10.1038/s41590-024-01945-3. Epub 2024 Sep 2. Nat Immunol. 2024. PMID: 39223350
Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk.
Ying P, Chen C, Lu Z, Chen S, Zhang M, Cai Y, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Tian W, Yang Z, Liu J, Huang C, Yang X, Xu B, Li H, Zhu X, Li N, Li B, Wei Y, Zhu Y, Tian J, Miao X. Ying P, et al. Among authors: li y, li h, li n, li b. Nat Commun. 2023 Sep 25;14(1):5958. doi: 10.1038/s41467-023-41690-z. Nat Commun. 2023. PMID: 37749132 Free PMC article.
Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk.
Tian J, Chen C, Rao M, Zhang M, Lu Z, Cai Y, Ying P, Li B, Wang H, Wang L, Li Y, Huang J, Fan L, Cai X, Ning C, Li Y, Zhang F, Wang W, Jiang Y, Liu Y, Wang M, Li H, Huang C, Yang Z, Chang J, Zhu Y, Yang X, Miao X. Tian J, et al. Among authors: li y, li h, li b. Cancer Res. 2022 Jun 6;82(11):2084-2096. doi: 10.1158/0008-5472.CAN-21-4367. Cancer Res. 2022. PMID: 35363263
Pan-Cancer Analysis of Microbiome Quantitative Trait Loci.
Chen C, Cai Y, Liu Y, Chen S, Li Y, Zhang F, Zhang M, Lu Z, Ying P, Huang J, Fan L, Cai X, Ning C, Wang W, Jiang Y, Zhang H, Yang S, Wang Z, Wang X, Zhang S, Huang C, Xu B, Fu Z, Song Q, Jin M, Chen K, Chen H, Dai M, Miao X, Yang X, Zhu Y, Tian J. Chen C, et al. Among authors: li y. Cancer Res. 2022 Oct 4;82(19):3449-3456. doi: 10.1158/0008-5472.CAN-22-1854. Cancer Res. 2022. PMID: 35972351
Saturated fatty acid intake, genetic risk and colorectal cancer incidence: A large-scale prospective cohort study.
Fan L, Cai Y, Wang H, Zhang H, Chen C, Zhang M, Lu Z, Li Y, Zhang F, Ning C, Wang W, Liu Y, Li H, Li G, Peng J, Hu K, Li B, Huang C, Yang X, Wei Y, Zhu Y, Jin M, Miao X, Tian J. Fan L, et al. Among authors: li y, li g, li h, li b. Int J Cancer. 2023 Aug 1;153(3):499-511. doi: 10.1002/ijc.34544. Epub 2023 Apr 23. Int J Cancer. 2023. PMID: 37087737
HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction.
Lu Z, Fan L, Zhang F, Huang C, Cai Y, Chen C, Li G, Zhang M, Huang J, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Ye T, Liu J, Yang X, Xu B, Zhu Y, Zhong R, Li H, Tian J, Li B, Miao X. Lu Z, et al. Among authors: li y, li g, li h, li b. Arch Toxicol. 2023 Jul;97(7):2015-2028. doi: 10.1007/s00204-023-03494-4. Epub 2023 May 28. Arch Toxicol. 2023. PMID: 37245169
Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms.
Zhang M, Chen C, Lu Z, Cai Y, Li Y, Zhang F, Liu Y, Chen S, Zhang H, Yang S, Gen H, Jiang Y, Ning C, Huang J, Wang W, Fan L, Zhang Y, Jin M, Han J, Xiong Z, Cai M, Liu J, Huang C, Yang X, Xu B, Li H, Li B, Zhu X, Wei Y, Zhu Y, Tian J, Miao X. Zhang M, et al. Among authors: li y, li h, li b. Gastroenterology. 2023 Nov;165(5):1151-1167. doi: 10.1053/j.gastro.2023.07.019. Epub 2023 Aug 3. Gastroenterology. 2023. PMID: 37541527
Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci.
Li B, Cai Y, Chen C, Li G, Zhang M, Lu Z, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Zhu Z, Xu B, Li H, Li H, Jin M, Wang X, Zhang S, Liu J, Huang C, Yang X, Wei Y, Zhu Y, Tian J, Miao X. Li B, et al. Among authors: li y, li g, li h. Cancer Res. 2023 Nov 1;83(21):3650-3666. doi: 10.1158/0008-5472.CAN-23-0251. Cancer Res. 2023. PMID: 37669142
Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.
Ning C, Fan L, Jin M, Wang W, Hu Z, Cai Y, Chen L, Lu Z, Zhang M, Chen C, Li Y, Zhang F, Wang W, Liu Y, Chen S, Jiang Y, He C, Wang Z, Chen X, Li H, Li G, Ma Q, Geng H, Tian W, Zhang H, Liu B, Xia Q, Yang X, Liu Z, Li B, Zhu Y, Li X, Zhang S, Tian J, Miao X. Ning C, et al. Among authors: li y, li g, li h, li x, li b. Nat Commun. 2023 Nov 30;14(1):7900. doi: 10.1038/s41467-023-43771-5. Nat Commun. 2023. PMID: 38036550 Free PMC article.
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