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Design of novel and highly selective SARS-CoV-2 main protease inhibitors.
Poli ANR, Tietjen I, Nandwana NK, Cassel J, Messick TE, Register ET, Keeney F, Rajaiah R, Verma AK, Pandey K, Acharya A, Byrareddy SN, Montaner LJ, Salvino JM. Poli ANR, et al. Among authors: cassel j. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0056224. doi: 10.1128/aac.00562-24. Epub 2024 Sep 3. Antimicrob Agents Chemother. 2024. PMID: 39225484 Free PMC article.
Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.
Matos-Hernández ML, Samples R, Dyer G, Casimir Montán VM, Morales-Colón CA, Salvino JM, Montaner LJ, Cassel JA, Messick TE, Tietjen I, Caro-Diaz EJE. Matos-Hernández ML, et al. Among authors: cassel ja. J Nat Prod. 2024 Jun 28;87(6):1513-1520. doi: 10.1021/acs.jnatprod.3c01071. Epub 2024 May 23. J Nat Prod. 2024. PMID: 38781491
Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor.
Williams DE, Cassel J, Zhu JL, Yang JX, de Voogd NJ, Matainaho T, Salvino JM, Wang YA, Montaner LJ, Tietjen I, Andersen RJ. Williams DE, et al. Among authors: cassel j. J Nat Prod. 2023 Mar 24;86(3):582-588. doi: 10.1021/acs.jnatprod.2c01030. Epub 2023 Jan 19. J Nat Prod. 2023. PMID: 36657039 Free PMC article.
Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression.
Tcyganov EN, Kwak T, Yang X, Poli ANR, Hart C, Bhuniya A, Cassel J, Kossenkov A, Auslander N, Lu L, Sharma P, Mendoza MGC, Zhigarev D, Cadungog MG, Jean S, Chatterjee-Paer S, Weiner D, Donthireddy L, Bristow B, Zhang R, Tyurin VA, Tyurina YY, Bayir H, Kagan VE, Salvino JM, Montaner LJ. Tcyganov EN, et al. Among authors: cassel j. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593562. doi: 10.1101/2024.05.10.593562. bioRxiv. 2024. PMID: 38798466 Free PMC article. Preprint.
466 results