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Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.
Lee AA, Amick I, Aschenbrenner JC, Barr HM, Benjamin J, Brandis A, Cohen G, Diaz-Tapia R, Duberstein S, Dixon J, Cousins D, Fairhead M, Fearon D, Frick J, Gayvert J, Godoy AS, Griffin EJ, Huber K, Koekemoer L, Lahav N, Marples PG, McGovern BL, Mehlman T, Robinson MC, Singh U, Szommer T, Tomlinson CWE, Vargo T, von Delft F, Wang S, White K, Williams E, Winokan M. Lee AA, et al. Among authors: koekemoer l. bioRxiv [Preprint]. 2024 Aug 21:2024.08.19.608619. doi: 10.1101/2024.08.19.608619. bioRxiv. 2024. PMID: 39229055 Free PMC article. Preprint.
A review of historical trends in Anopheles gambiae Giles (Diptera: Culicidae) complex composition, collection trends and environmental effects from 2009 to 2021 in Mpumalanga province, South Africa.
Noeth KP, Kaiser ML, Mashatola T, Dahan-Moss YL, Matamba PA, Spillings B, Christian R, Erlank E, Tshikae BP, Jamesboy E, Sibambo S, Nkosi BG, Silawu BT, Mkhabela LJ, Ndlovu FS, Mgwenya TP, Coetzee M, Brooke BD, Koekemoer LL, Munhenga G, Oliver SV. Noeth KP, et al. Among authors: koekemoer ll. Med Vet Entomol. 2024 Sep 5. doi: 10.1111/mve.12761. Online ahead of print. Med Vet Entomol. 2024. PMID: 39238107
Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening.
Aschenbrenner JC, de Godoy AS, Fairhead M, Tomlinson CWE, Winokan M, Balcomb BH, Capkin E, Chandran AV, Golding M, Koekemoer L, Lithgo RM, Marples PG, Ni X, Thompson W, Wild C, Xavier ME, Fearon D, von Delft F. Aschenbrenner JC, et al. Among authors: koekemoer l. bioRxiv [Preprint]. 2024 Aug 23:2024.08.23.609196. doi: 10.1101/2024.08.23.609196. bioRxiv. 2024. PMID: 39229067 Free PMC article. Preprint.
The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against Plasmodium falciparum.
Watson SJ, van der Watt ME, Theron A, Reader J, Tshabalala S, Erlank E, Koekemoer LL, Naude M, Stampolaki M, Adewole F, Sadowska K, Pérez-Lozano P, Turcu AL, Vázquez S, Ko J, Mazurek B, Singh D, Malwal SR, Njoroge M, Chibale K, Onajole OK, Kolocouris A, Oldfield E, Birkholtz LM. Watson SJ, et al. Among authors: koekemoer ll. ACS Infect Dis. 2024 Sep 13;10(9):3358-3367. doi: 10.1021/acsinfecdis.4c00461. Epub 2024 Aug 14. ACS Infect Dis. 2024. PMID: 39143042 Free PMC article.
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Barrett JR, Pipini D, Wright ND, Cooper AJR, Gorini G, Quinkert D, Lias AM, Davies H, Rigby CA, Aleshnick M, Williams BG, Bradshaw WJ, Paterson NG, Martinson T, Kirtley P, Picard L, Wiggins CD, Donnellan FR, King LDW, Wang LT, Popplewell JF, Silk SE, de Ruiter Swain J, Skinner K, Kotraiah V, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Minassian AM, Lauffenburger DA, Miura K, Long CA, Wilder BK, Koekemoer L, Tan J, Nielsen CM, McHugh K, Draper SJ. Barrett JR, et al. Among authors: koekemoer l. Cell. 2024 Sep 5;187(18):4964-4980.e21. doi: 10.1016/j.cell.2024.06.015. Epub 2024 Jul 25. Cell. 2024. PMID: 39059380 Free article.
Genetic markers associated with the widespread insecticide resistance in malaria vector Anopheles funestus populations across Tanzania.
Odero JO, Nambunga IH, Masalu JP, Mkandawile G, Bwanary H, Hape EE, Njalambaha RM, Tungu P, Ngowo HS, Kaindoa EW, Mapua SA, Kahamba NF, Nelli L, Wondji C, Koekemoer LL, Weetman D, Ferguson HM, Baldini F, Okumu FO. Odero JO, et al. Among authors: koekemoer ll. Parasit Vectors. 2024 May 17;17(1):230. doi: 10.1186/s13071-024-06315-4. Parasit Vectors. 2024. PMID: 38760849 Free PMC article.
158 results