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Page 1
Chronic innate immune impairment and ZIKV persistence in the gastrointestinal tract during SIV infection in pigtail macaques.
Tisoncik-Go J, Lewis TB, Whitmore LS, Voss K, Niemeyer S, Dai J, Kim P, Hubbell K, Iwayama N, Ahrens C, Wangari S, Murnane R, Edlefsen PT, Guerriero KA, Gale M Jr, Fuller DH, O'Connor MA. Tisoncik-Go J, et al. Among authors: edlefsen pt. bioRxiv [Preprint]. 2024 Aug 23:2024.08.23.609309. doi: 10.1101/2024.08.23.609309. bioRxiv. 2024. PMID: 39229223 Free PMC article. Preprint.
A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned.
Oâ Connor MA, Hawman DW, Meade-White K, Leventhal S, Song W, Randall S, Archer J, Lewis TB, Brown B, Iwayama N, Ahrens C, Garrison W, Wangari S, Guerriero KA, Hanley P, Lovaglio J, Saturday G, Edlefsen PT, Khandhar A, Feldmann H, Fuller DH, Erasmus JH. Oâ Connor MA, et al. Among authors: edlefsen pt. bioRxiv [Preprint]. 2022 Aug 9:2022.08.08.503239. doi: 10.1101/2022.08.08.503239. bioRxiv. 2022. Update in: PLoS Pathog. 2023 Apr 19;19(4):e1011298. doi: 10.1371/journal.ppat.1011298 PMID: 35982677 Free PMC article. Updated. Preprint.
Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model.
Plumlee CR, Barrett HW, Shao DE, Lien KA, Cross LM, Cohen SB, Edlefsen PT, Urdahl KB. Plumlee CR, et al. Among authors: edlefsen pt. bioRxiv [Preprint]. 2023 Jun 16:2023.03.22.533820. doi: 10.1101/2023.03.22.533820. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Nov 27;19(11):e1011825. doi: 10.1371/journal.ppat.1011825 PMID: 36993415 Free PMC article. Updated. Preprint.
A HIV-1 Gp41 Peptide-Liposome Vaccine Elicits Neutralizing Epitope-Targeted Antibody Responses in Healthy Individuals.
Erdmann NB, Williams WB, Walsh SR, Grunenberg N, Edlefsen PT, Goepfert PA, Cain DW, Cohen KW, Maenza J, Mayer KH, Tieu HV, Sobieszczyk ME, Swann E, Lu H, De Rosa SC, Sagawa Z, Moody MA, Fox CB, Ferrari G, Edwards RJ, Acharya P, Alam SM, Parks R, Barr M, Tomaras GD, Montefiori DC, Gilbert PB, McElrath MJ, Corey L, Haynes BF, Baden LR; NIAID HVTN 133 Study Group. Erdmann NB, et al. Among authors: edlefsen pt. medRxiv [Preprint]. 2024 Mar 18:2024.03.15.24304305. doi: 10.1101/2024.03.15.24304305. medRxiv. 2024. PMID: 38562833 Free PMC article. Preprint.
Infectious Morbidity and All-cause Mortality of Infants HIV-exposed Uninfected Compared to Infants HIV-unexposed Uninfected in Botswana.
Dubois MM, Jao J, Sun S, Legbedze J, Schenkel S, Mmasa N, Kgole SW, Masasa G, Happel AU, Iwase SC, Haghighat R, Moyo S, Sharma TS, Edlefsen PT, Shao D, Jaspan H, Powis KM. Dubois MM, et al. Among authors: edlefsen pt. Pediatr Infect Dis J. 2024 Oct 31. doi: 10.1097/INF.0000000000004603. Online ahead of print. Pediatr Infect Dis J. 2024. PMID: 39486012
Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence.
Varco-Merth B, Chaunzwa M, Duell DM, Marenco A, Goodwin W, Dannay R, Nekorchuk M, Shao D, Busman-Sahay K, Fennessey CM, Silipino L, Hull M, Bosche WJ, Fast R, Oswald K, Shoemaker R, Bochart R, MacAllister R, Labriola CS, Smedley JV, Axthelm MK, Davenport MP, Edlefsen PT, Estes JD, Keele BF, Lifson JD, Lewin SR, Picker LJ, Okoye AA. Varco-Merth B, et al. Among authors: edlefsen pt. PLoS Pathog. 2024 Aug 22;20(8):e1012496. doi: 10.1371/journal.ppat.1012496. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39173097 Free PMC article.
Observational study of effects of HIV acquisition and antiretroviral treatment on biomarkers of systemic immune activation.
Kosmider E, Wallner J, Gervassi A, Bender Ignacio RA, Pinto-Santini D, Gornalusse G, Pandey U, Hladik F, Edlefsen PT, Lama JR, Duerr AC, Frenkel LM. Kosmider E, et al. Among authors: edlefsen pt. PLoS One. 2024 Jul 8;19(7):e0288895. doi: 10.1371/journal.pone.0288895. eCollection 2024. PLoS One. 2024. PMID: 38976697 Free PMC article.
Antigen specificities and proviral integration sites differ in HIV-infected cells by timing of antiretroviral treatment initiation.
Joy J, Gervassi A, Chen L, Kirshenbaum B, Styrchak S, Ko D, McLaughlin S, Shao D, Kosmider E, Edlefsen PT, Maenza J, Collier AC, Mullins JI, Horton H, Frenkel LM. Joy J, et al. Among authors: edlefsen pt. J Clin Invest. 2024 Jun 4;134(14):e159569. doi: 10.1172/JCI159569. J Clin Invest. 2024. PMID: 38833307 Free PMC article.
A non-invasive method to sample immune cells in the lower female genital tract using menstrual discs.
Quinn Peters M, Domenjo-Vila E, Carlson M, Armistead B, Edlefsen PT, Gasper M, Dabee S, Whidbey C, Jaspan HB, Prlic M, Harrington WE. Quinn Peters M, et al. Among authors: edlefsen pt. bioRxiv [Preprint]. 2024 Feb 10:2023.11.16.567469. doi: 10.1101/2023.11.16.567469. bioRxiv. 2024. Update in: Immunohorizons. 2024 Feb 1;8(2):182-192. doi: 10.4049/immunohorizons.2300105 PMID: 38370684 Free PMC article. Updated. Preprint.
68 results