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Page 1
Regulatory considerations for developing remote measurement technologies for Alzheimer's disease research.
Erdemli G, Grammatikopoulou M, Wagner B, Vairavan S, Curcic J, Aarsland D, Wittenberg G, Nikolopoulos S, Muurling M, Froehlich H, de Boer C, Shanbhag NM, Nies VJM, Coello N, Gove D, Diaz A, Foy S, Dartee W, Brem AK. Erdemli G, et al. Among authors: nies vjm. NPJ Digit Med. 2024 Sep 4;7(1):232. doi: 10.1038/s41746-024-01211-8. NPJ Digit Med. 2024. PMID: 39232033 Free PMC article.
Digital endpoints in clinical trials of Alzheimer's disease and other neurodegenerative diseases: challenges and opportunities.
Brem AK, Kuruppu S, de Boer C, Muurling M, Diaz-Ponce A, Gove D, Curcic J, Pilotto A, Ng WF, Cummins N, Malzbender K, Nies VJM, Erdemli G, Graeber J, Narayan VA, Rochester L, Maetzler W, Aarsland D. Brem AK, et al. Among authors: nies vjm. Front Neurol. 2023 Jun 15;14:1210974. doi: 10.3389/fneur.2023.1210974. eCollection 2023. Front Neurol. 2023. PMID: 37435159 Free PMC article. Review.
Autocrine FGF1 signaling promotes glucose uptake in adipocytes.
Nies VJM, Struik D, Liu S, Liu W, Kruit JK, Downes M, van Zutphen T, Verkade HJ, Evans RM, Jonker JW. Nies VJM, et al. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2122382119. doi: 10.1073/pnas.2122382119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161959 Free PMC article.
IMI European Lead Factory - democratizing access to high-throughput screening.
Jones PS, Boucharens S, McElroy SP, Morrison A, Honarnejad S, van Boeckel S, van den Hurk H, Basting D, Hüser J, Jaroch S, Ottow E, Benningshof J, Folmer RHA, Leemhuis F, Kramer-Verhulst PM, Nies VJM, Orrling KM, Rijnders T, Pfander C, Engkvist O, Pairaudeau G, Simpson PB, Ortholand JY, Roche D, Dömling A, Kühnert SM, Roevens PWM, van Vlijmen H, van Wanrooij EJA, Verbruggen C, Nussbaumer P, Ovaa H, van der Stelt M, Simonsen KB, Tagmose L, Waldmann H, Duffy J, Finsinger D, Jurzak M, Burgess-Brown NA, Lee WH, Rutjes FPJT, Haag H, Kallus C, Mors H, Dorval T, Lesur B, Ramon Olayo F, Hamza D, Jones G, Pearce C, Piechot A, Tzalis D, Clausen MH, Davis J, Derouane D, Vermeiren C, Kaiser M, Stockman RA, Barrault DV, Pannifer AD, Swedlow JR, Nelson AS, Orru RVA, Ruijter E, van Helden SP, Li VM, Vries T, de Vlieger JSB. Jones PS, et al. Among authors: nies vjm. Nat Rev Drug Discov. 2022 Apr;21(4):245-246. doi: 10.1038/d41573-021-00196-3. Nat Rev Drug Discov. 2022. PMID: 34907316 No abstract available.
Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study.
Muurling M, de Boer C, Kozak R, Religa D, Koychev I, Verheij H, Nies VJM, Duyndam A, Sood M, Fröhlich H, Hannesdottir K, Erdemli G, Lucivero F, Lancaster C, Hinds C, Stravopoulos TG, Nikolopoulos S, Kompatsiaris I, Manyakov NV, Owens AP, Narayan VA, Aarsland D, Visser PJ; RADAR-AD Consortium. Muurling M, et al. Among authors: nies vjm. Alzheimers Res Ther. 2021 Apr 23;13(1):89. doi: 10.1186/s13195-021-00825-4. Alzheimers Res Ther. 2021. PMID: 33892789 Free PMC article.
TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans.
Nies VJM, Struik D, Wolfs MGM, Rensen SS, Szalowska E, Unmehopa UA, Fluiter K, van der Meer TP, Hajmousa G, Buurman WA, Greve JW, Rezaee F, Shiri-Sverdlov R, Vonk RJ, Swaab DF, Wolffenbuttel BHR, Jonker JW, van Vliet-Ostaptchouk JV. Nies VJM, et al. Int J Obes (Lond). 2018 Mar;42(3):376-383. doi: 10.1038/ijo.2017.214. Epub 2017 Aug 30. Int J Obes (Lond). 2018. PMID: 28852204
Fibroblast Growth Factor Signaling in Metabolic Regulation.
Nies VJ, Sancar G, Liu W, van Zutphen T, Struik D, Yu RT, Atkins AR, Evans RM, Jonker JW, Downes MR. Nies VJ, et al. Front Endocrinol (Lausanne). 2016 Jan 19;6:193. doi: 10.3389/fendo.2015.00193. eCollection 2015. Front Endocrinol (Lausanne). 2016. PMID: 26834701 Free PMC article. Review.