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Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury.
Subramanian A, Vernon KA, Zhou Y, Marshall JL, Alimova M, Arevalo C, Zhang F, Slyper M, Waldman J, Montesinos MS, Dionne D, Nguyen LT, Cuoco MS, Dubinsky D, Purnell J, Keller K, Sturner SH, Grinkevich E, Ghoshal A, Kotek A, Trivioli G, Richoz N, Humphrey MB, Darby IG, Miller SJ, Xu Y, Weins A, Chloe-Villani A, Chang SL, Kretzler M, Rosenblatt-Rosen O, Shaw JL, Zimmerman KA, Clatworthy MR, Regev A, Greka A. Subramanian A, et al. Among authors: kretzler m. Cell Rep. 2024 Jun 25;43(6):114253. doi: 10.1016/j.celrep.2024.114253. Epub 2024 May 22. Cell Rep. 2024. PMID: 38781074 Free PMC article.
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome.
Gillies CE, Putler R, Menon R, Otto E, Yasutake K, Nair V, Hoover P, Lieb D, Li S, Eddy S, Fermin D, McNulty MT; Nephrotic Syndrome Study Network (NEPTUNE); Hacohen N, Kiryluk K, Kretzler M, Wen X, Sampson MG. Gillies CE, et al. Among authors: kretzler m. Am J Hum Genet. 2018 Aug 2;103(2):232-244. doi: 10.1016/j.ajhg.2018.07.004. Epub 2018 Jul 26. Am J Hum Genet. 2018. PMID: 30057032 Free PMC article.
Neuronally differentiated macula densa cells regulate tissue remodeling and regeneration in the kidney.
Gyarmati G, Shroff UN, Riquier-Brison A, Desposito D, Ju W, Stocker SD, Izuhara A, Deepak S, Becerra Calderon A, Burford JL, Kadoya H, Moon JY, Chen Y, Rinschen MM, Ahmadi N, Lau L, Biemesderfer D, James AW, Minichiello L, Zlokovic BV, Gill IS, Kretzler M, Peti-Peterdi J. Gyarmati G, et al. Among authors: kretzler m. J Clin Invest. 2024 Apr 10;134(11):e174558. doi: 10.1172/JCI174558. J Clin Invest. 2024. PMID: 38598837 Free PMC article.
Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease.
Lay AC, Tran VDT, Nair V, Betin V, Hurcombe JA, Barrington AF, Pope RJ, Burdet F, Mehl F, Kryvokhyzha D, Ahmad A, Sinton MC, Lewis P, Wilson MC, Menon R, Otto E, Heesom KJ, Ibberson M, Looker HC, Nelson RG, Ju W, Kretzler M, Satchell SC, Gomez MF, Coward RJM; BEAt-DKD consortium. Lay AC, et al. Among authors: kretzler m. Nat Commun. 2024 Nov 19;15(1):10018. doi: 10.1038/s41467-024-54089-1. Nat Commun. 2024. PMID: 39562547 Free PMC article.
Association of urinary EGF, FABP3, and VCAM1 levels with the progression of early diabetic kidney disease.
Keller F, Denicolò S, Leierer J, Kruus M, Heinzel A, Kammer M, Ju W, Nair V, Burdet F, Ibberson M, Menon R, Otto E, Choi YJ, Pyle L, Ladd P, Bjornstad PM, Eder S, Rosivall L, Mark PB, Wiecek A, Heerspink HJL, Kretzler M, Oberbauer R, Mayer G, Perco P. Keller F, et al. Among authors: kretzler m. Kidney Blood Press Res. 2024 Nov 7:1-21. doi: 10.1159/000542267. Online ahead of print. Kidney Blood Press Res. 2024. PMID: 39510044 Free article.
APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans.
Gbadegesin RA, Ulasi I, Ajayi S, Raji Y, Olanrewaju T, Osafo C, Ademola AD, Asinobi A, Winkler CA, Burke D, Arogundade F, Ekem I, Plange-Rhule J, Mamven M, Matekole M, Amodu O, Cooper R, Antwi S, Adeyemo AA, Ilori TO, Adabayeri V, Nyarko A, Ghansah A, Amira T, Solarin A, Awobusuyi O, Kimmel PL, Brosius FC, Makusidi M, Odenigbo U, Kretzler M, Hodgin JB, Pollak MR, Boima V, Freedman BI, Palmer ND, Collins B, Phadnis M, Smith J, Agwai CI, Okoye O, Abdu A, Wilson J, Williams W, Salako BL, Parekh RS, Tayo B, Adu D, Ojo A; H3Africa Kidney Disease Research Network. Gbadegesin RA, et al. Among authors: kretzler m. N Engl J Med. 2024 Oct 26. doi: 10.1056/NEJMoa2404211. Online ahead of print. N Engl J Med. 2024. PMID: 39465900
A Novel Role for FERM Domain-Containing Protein 3 (FRMD3) in CKD.
Kennedy C, Doyle R, Gough O, Mcevoy C, Anallen SM, Hughes M, Sheng X, Crifo B, Andrews D, Gaffney A, Rodriguez J, Kennedy S, Dillon E, Crean D, Zhang W, Yi Z, Nair V, Susztak K, Hirschhorn J, Florez J, Groop PH, Sandholm N, Kretzler M, Mckay GJ, Mcknight AJ, Maxwell AP, Matallanas D, Dorman A, Martin F, Conlon PJ, Sadlier DM, Brennan E, Godson C; Genie Consortium. Kennedy C, et al. Among authors: kretzler m. Kidney360. 2024 Oct 16. doi: 10.34067/KID.0000000602. Online ahead of print. Kidney360. 2024. PMID: 39450948 Free article.
Attenuated kidney oxidative metabolism in young adults with type 1 diabetes.
Choi YJ, Richard G, Zhang G, Hodgin JB, Demeke DS, Yang Y, Schaub JA, Tamayo IM, Gurung BK, Naik AS, Nair V, Birznieks C, MacDonald A, Narongkiatikhun P, Gross S, Driscoll L, Flynn M, Tommerdahl K, Nadeau KJ, Shah VN, Vigers T, Snell-Bergeon JK, Kendrick J, van Raalte DH, Li LP, Prasad P, Ladd P, Chin BB, Cherney DZ, McCown PJ, Alakwaa F, Otto EA, Brosius FC, Saulnier PJ, Puelles VG, Goodrich JA, Street K, Venkatachalam MA, Ruiz A, de Boer IH, Nelson RG, Pyle L, Blondin DP, Sharma K, Kretzler M, Bjornstad P. Choi YJ, et al. Among authors: kretzler m. J Clin Invest. 2024 Oct 22:e183984. doi: 10.1172/JCI183984. Online ahead of print. J Clin Invest. 2024. PMID: 39436695 Free article.
473 results