LRRC8A is essential for swelling-activated chloride current and for regulatory volume decrease in astrocytes.
Formaggio F, Saracino E, Mola MG, Rao SB, Amiry-Moghaddam M, Muccini M, Zamboni R, Nicchia GP, Caprini M, Benfenati V.
Formaggio F, et al. Among authors: caprini m.
FASEB J. 2019 Jan;33(1):101-113. doi: 10.1096/fj.201701397RR. Epub 2018 Jun 29.
FASEB J. 2019.
PMID: 29957062
Collectively, our results suggest that LRRC8A is an essential subunit of VRAC and a key factor for astroglial volume homeostasis.-Formaggio, F., Saracino, E., Mola, M. G., Rao, S. B., Amiry-Moghaddam, M., Muccini, M., Zamboni, R., Nicchia, G. P., Caprini …
Collectively, our results suggest that LRRC8A is an essential subunit of VRAC and a key factor for astroglial volume homeostasis.-Formaggio, …