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The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.
Richard J, Grunst MW, Niu L, Díaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M; Guillaume-Beaudoin-Buissières; Gottumukkala S, Li W, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D, Smith AB 3rd, Mothes W, Munro JB, Pazgier M, Finzi A. Richard J, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2024 Aug 27:2024.08.27.609961. doi: 10.1101/2024.08.27.609961. bioRxiv. 2024. PMID: 39253431 Free PMC article. Preprint.
Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike.
Prévost J, Gasser R, Beaudoin-Bussières G, Richard J, Duerr R, Laumaea A, Anand SP, Goyette G, Benlarbi M, Ding S, Medjahed H, Lewin A, Perreault J, Tremblay T, Gendron-Lepage G, Gauthier N, Carrier M, Marcoux D, Piché A, Lavoie M, Benoit A, Loungnarath V, Brochu G, Haddad E, Stacey HD, Miller MS, Desforges M, Talbot PJ, Gould Maule GT, Côté M, Therrien C, Serhir B, Bazin R, Roger M, Finzi A. Prévost J, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2020 Jul 30:2020.06.08.140244. doi: 10.1101/2020.06.08.140244. bioRxiv. 2020. Update in: Cell Rep Med. 2020 Oct 20;1(7):100126. doi: 10.1016/j.xcrm.2020.100126 PMID: 32577637 Free PMC article. Updated. Preprint.
Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset.
Anand SP, Prévost J, Nayrac M, Beaudoin-Bussières G, Benlarbi M, Gasser R, Brassard N, Laumaea A, Gong SY, Bourassa C, Brunet-Ratnasingham E, Medjahed H, Gendron-Lepage G, Goyette G, Gokool L, Morrisseau C, Bégin P, Martel-Laferrière V, Tremblay C, Richard J, Bazin R, Duerr R, Kaufmann DE, Finzi A. Anand SP, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2021 Jan 25:2021.01.25.428097. doi: 10.1101/2021.01.25.428097. bioRxiv. 2021. Update in: Cell Rep Med. 2021 Jun 15;2(6):100290. doi: 10.1016/j.xcrm.2021.100290 PMID: 33532774 Free PMC article. Updated. Preprint.
A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2021 Mar 18:2021.03.18.435972. doi: 10.1101/2021.03.18.435972. bioRxiv. 2021. PMID: 33758857 Free PMC article. Preprint.
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy.
Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Ullah I, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2021 Jun 28:2021.03.22.436337. doi: 10.1101/2021.03.22.436337. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2143-2158.e15. doi: 10.1016/j.immuni.2021.08.015 PMID: 33791699 Free PMC article. Updated. Preprint.
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: benlarbi m. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. Cell Host Microbe. 2021. PMID: 34133950 Free PMC article.
Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2.
Prévost J, Richard J, Gasser R, Ding S, Fage C, Anand SP, Adam D, Vergara NG, Tauzin A, Benlarbi M, Gong SY, Goyette G, Privé A, Moreira S, Charest H, Roger M, Mothes W, Pazgier M, Brochiero E, Boivin G, Abrams CF, Schön A, Finzi A. Prévost J, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2021 Jul 9:2021.07.09.451812. doi: 10.1101/2021.07.09.451812. bioRxiv. 2021. Update in: J Biol Chem. 2021 Oct;297(4):101151. doi: 10.1016/j.jbc.2021.101151 PMID: 34268505 Free PMC article. Updated. Preprint.
Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen.
Nayrac M, Dubé M, Sannier G, Nicolas A, Marchitto L, Tastet O, Tauzin A, Brassard N, Beaudoin-Bussières G, Vézina D, Gong SY, Benlarbi M, Gasser R, Laumaea A, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Ortega-Delgado GG, Laporte M, Niessl J, Gokool L, Morrisseau C, Arlotto P, Richard J, Tremblay C, Martel-Laferrière V, Finzi A, Kaufmann DE. Nayrac M, et al. Among authors: benlarbi m. bioRxiv [Preprint]. 2021 Dec 21:2021.12.18.473317. doi: 10.1101/2021.12.18.473317. bioRxiv. 2021. Update in: Cell Rep. 2022 Jun 28;39(13):111013. doi: 10.1016/j.celrep.2022.111013 PMID: 34981046 Free PMC article. Updated. Preprint.
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, Gasser R, Chatterjee D, Vézina D, Goyette G, Richard J, Zhou F, Stamatatos L, McGuire AT, Charest H, Roger M, Pozharski E, Kumar P, Mothes W, Uchil PD, Pazgier M, Finzi A. Beaudoin-Bussières G, et al. Among authors: benlarbi m. Cell Rep. 2022 Feb 15;38(7):110368. doi: 10.1016/j.celrep.2022.110368. Epub 2022 Jan 25. Cell Rep. 2022. PMID: 35123652 Free PMC article.
62 results