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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: de jesus df. Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. Epub 2024 Sep 9. Cell Metab. 2024. PMID: 39255799
Epigenetic modifiers of islet function and mass.
De Jesus DF, Kulkarni RN. De Jesus DF, et al. Trends Endocrinol Metab. 2014 Dec;25(12):628-36. doi: 10.1016/j.tem.2014.08.006. Epub 2014 Sep 19. Trends Endocrinol Metab. 2014. PMID: 25246382 Review.
m 6 A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: de jesus df. bioRxiv [Preprint]. 2023 May 26:2023.05.26.542169. doi: 10.1101/2023.05.26.542169. bioRxiv. 2023. Update in: Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. PMID: 37292780 Free PMC article. Updated. Preprint.
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Basile G, Vetere A, Hu J, Ijaduola O, Zhang Y, Liu KC, Eltony AM, De Jesus DF, Fukuda K, Doherty G, Leech CA, Chepurny OG, Holz GG, Yun SH, Andersson O, Choudhary A, Wagner BK, Kulkarni RN. Basile G, et al. Among authors: de jesus df. Cell Metab. 2023 Jul 11;35(7):1242-1260.e9. doi: 10.1016/j.cmet.2023.05.007. Epub 2023 Jun 19. Cell Metab. 2023. PMID: 37339634 Free PMC article.
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes.
De Jesus DF, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN. De Jesus DF, et al. Nat Cell Biol. 2024 Mar;26(3):421-437. doi: 10.1038/s41556-024-01368-0. Epub 2024 Feb 26. Nat Cell Biol. 2024. PMID: 38409327 Free PMC article.
34 results