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Page 1
m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: pihlajamaki j. Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. Epub 2024 Sep 9. Cell Metab. 2024. PMID: 39255799
m 6 A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis.
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM, Wei S, Ijaduola O, Blüher M, Cypess AM, Pihlajamäki J, Tseng YH, He C, Kulkarni RN. Xiao L, et al. Among authors: pihlajamaki j. bioRxiv [Preprint]. 2023 May 26:2023.05.26.542169. doi: 10.1101/2023.05.26.542169. bioRxiv. 2023. Update in: Cell Metab. 2024 Oct 1;36(10):2207-2227.e9. doi: 10.1016/j.cmet.2024.08.006. PMID: 37292780 Free PMC article. Updated. Preprint.
IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids.
Sasidharan K, Caddeo A, Jamialahmadi O, Noto FR, Tomasi M, Malvestiti F, Ciociola E, Tavaglione F, Mancina RM, Cherubini A, Bianco C, Mirarchi A, Männistö V, Pihlajamäki J, Kärjä V, Grimaudo S, Luukkonen PK, Qadri S, Yki-Järvinen H, Petta S, Manfrini S, Vespasiani-Gentilucci U, Bruni V, Valenti L, Romeo S. Sasidharan K, et al. Among authors: pihlajamaki j. Cell Rep Med. 2024 Jan 16;5(1):101352. doi: 10.1016/j.xcrm.2023.101352. Cell Rep Med. 2024. PMID: 38232700 Free PMC article.
Corrigendum to "SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease" [J Hepatol 80 (2024) 10-19].
Salomone F, Pipitone RM, Longo M, Malvestiti F, Amorini AM, Distefano A, Casirati E, Ciociola E, Iraci N, Leggio L, Zito R, Vicario N, Saoca C, Männistö V, Pihlajamäki J, Qadri S, Yki-Järvinen H, Romeo S, Pennisi G, Cabibi D, Lazzarino G, Fracanzani AL, Dongiovanni P, Valenti L, Petta S, Volti GL, Grimaudo S. Salomone F, et al. Among authors: pihlajamaki j. J Hepatol. 2024 Feb;80(2):378. doi: 10.1016/j.jhep.2023.12.002. Epub 2024 Jan 4. J Hepatol. 2024. PMID: 38182533 No abstract available.
Author Correction: Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women.
Cherubini A, Ostadreza M, Jamialahmadi O, Pelusi S, Rrapaj E, Casirati E, Passignani G, Norouziesfahani M, Sinopoli E, Baselli G, Meda C, Dongiovanni P, Dondossola D, Youngson N, Tourna A, Chokshi S, Bugianesi E; EPIDEMIC Study Investigators; Della Torre S, Prati D, Romeo S, Valenti L. Cherubini A, et al. Nat Med. 2024 Apr;30(4):1212. doi: 10.1038/s41591-024-02817-x. Nat Med. 2024. PMID: 38267549 Free PMC article. No abstract available.
An abdominal obesity missense variant in the adipocyte thermogenesis gene TBX15 is implicated in adaptation to cold in Finns.
Deal M, Kar A, Lee SHT, Alvarez M, Rajkumar S, Arasu UT, Kaminska D, Männistö V, Heinonen S, van der Kolk BW, Säiläkivi U, Saarinen T, Juuti A, Pihlajamäki J, Kaikkonen MU, Laakso M, Pietiläinen KH, Pajukanta P. Deal M, et al. Among authors: pihlajamaki j. Am J Hum Genet. 2024 Nov 7;111(11):2542-2560. doi: 10.1016/j.ajhg.2024.10.001. Am J Hum Genet. 2024. PMID: 39515300 Free PMC article.
Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet-An exploratory study.
Vaittinen M, Ilha M, Sehgal R, Lankinen MA, Ågren J, Käkelä P, Virtanen KA, Laakso M, Schwab U, Pihlajamäki J. Vaittinen M, et al. Among authors: pihlajamaki j. J Lipid Res. 2024 Oct;65(10):100638. doi: 10.1016/j.jlr.2024.100638. Epub 2024 Aug 31. J Lipid Res. 2024. PMID: 39218219 Free PMC article.
Protein Phosphatase 1 Regulatory Subunit 3 Beta rs4240624 Genotype Is Associated With Gallstones and With Significant Changes in Bile Lipidome.
Männistö VT, Kaminska D, Haal S, Asteljoki J, Luukkonen PK, Käkelä P, Tavaglione F, van Weeghel M, Neuvonen M, Niemi M, Romeo S, Nieuwdorp M, Pihlajamäki J, Groen AK. Männistö VT, et al. Among authors: pihlajamaki j. Gastro Hep Adv. 2024 Mar 12;3(5):594-601. doi: 10.1016/j.gastha.2024.03.005. eCollection 2024. Gastro Hep Adv. 2024. PMID: 39165418 Free PMC article.
Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease.
Lee SHT, Garske KM, Arasu UT, Kar A, Miao Z, Alvarez M, Koka A, Darci-Maher N, Benhammou JN, Pan DZ, Örd T, Kaminska D, Männistö V, Heinonen S, Wabitsch M, Laakso M, Agopian VG, Pisegna JR, Pietiläinen KH, Pihlajamäki J, Kaikkonen MU, Pajukanta P. Lee SHT, et al. Among authors: pihlajamaki j. EBioMedicine. 2024 Aug;106:105232. doi: 10.1016/j.ebiom.2024.105232. Epub 2024 Jul 10. EBioMedicine. 2024. PMID: 38991381 Free article.
270 results