Ciechanover A - Search Results

1

Inhibition of nucleo-cytoplasmic proteasome translocation by the aromatic amino acids or silencing Sestrin3-their sensing mediator-is tumor suppressive.

Livneh I, Fabre B, Goldhirsh G, Lulu C, Zinger A, Shammai Vainer Y, Kaduri M, Dahan A, Ziv T, Schroeder A, Ben-Neriah Y, Zohar Y, Cohen-Kaplan V, Ciechanover A. Livneh I, et al. Among authors: ciechanover a. Cell Death Differ. 2024 Oct;31(10):1242-1254. doi: 10.1038/s41418-024-01370-x. Epub 2024 Sep 12. Cell Death Differ. 2024. PMID: 39266717 Free PMC article.

2

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.

Alkalay I, Yaron A, Hatzubai A, Orian A, Ciechanover A, Ben-Neriah Y. Alkalay I, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10599-603. doi: 10.1073/pnas.92.23.10599. Proc Natl Acad Sci U S A. 1995. PMID: 7479848 Free PMC article.

3

The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators.

Ciechanover A, Laszlo A, Bercovich B, Stancovski I, Alkalay I, Ben-Neriah Y, Orian A. Ciechanover A, et al. Cold Spring Harb Symp Quant Biol. 1995;60:491-501. doi: 10.1101/sqb.1995.060.01.053. Cold Spring Harb Symp Quant Biol. 1995. PMID: 8824422 No abstract available.

4

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase.

Yaron A, Gonen H, Alkalay I, Hatzubai A, Jung S, Beyth S, Mercurio F, Manning AM, Ciechanover A, Ben-Neriah Y. Yaron A, et al. Among authors: ciechanover a. EMBO J. 1997 Nov 3;16(21):6486-94. doi: 10.1093/emboj/16.21.6486. EMBO J. 1997. PMID: 9351830 Free PMC article.

5

A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.

Breitschopf K, Bengal E, Ziv T, Admon A, Ciechanover A. Breitschopf K, et al. Among authors: ciechanover a. EMBO J. 1998 Oct 15;17(20):5964-73. doi: 10.1093/emboj/17.20.5964. EMBO J. 1998. PMID: 9774340 Free PMC article.

6

c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination.

Sionov RV, Coen S, Goldberg Z, Berger M, Bercovich B, Ben-Neriah Y, Ciechanover A, Haupt Y. Sionov RV, et al. Among authors: ciechanover a. Mol Cell Biol. 2001 Sep;21(17):5869-78. doi: 10.1128/MCB.21.17.5869-5878.2001. Mol Cell Biol. 2001. PMID: 11486026 Free PMC article.

7

The tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residue.

Ben-Saadon R, Fajerman I, Ziv T, Hellman U, Schwartz AL, Ciechanover A. Ben-Saadon R, et al. Among authors: ciechanover a. J Biol Chem. 2004 Oct 1;279(40):41414-21. doi: 10.1074/jbc.M407201200. Epub 2004 Jul 14. J Biol Chem. 2004. PMID: 15254040 Free article.

8

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting.

Ciechanover A. Ciechanover A. Cell Death Differ. 2005 Sep;12(9):1178-90. doi: 10.1038/sj.cdd.4401692. Cell Death Differ. 2005. PMID: 16094394 Review.

9

The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity.

Ben-Saadon R, Zaaroor D, Ziv T, Ciechanover A. Ben-Saadon R, et al. Among authors: ciechanover a. Mol Cell. 2006 Dec 8;24(5):701-711. doi: 10.1016/j.molcel.2006.10.022. Mol Cell. 2006. PMID: 17157253 Free article.

10

Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms.

de Bie P, Ciechanover A. de Bie P, et al. Among authors: ciechanover a. Cell Death Differ. 2011 Sep;18(9):1393-402. doi: 10.1038/cdd.2011.16. Epub 2011 Mar 4. Cell Death Differ. 2011. PMID: 21372847 Free PMC article. Review.

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