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Rigid crosslinking of the CD3 complex leads to superior T cell stimulation.
Nelson AD, Wang L, Laffey KG, Becher LRE, Parks CA, Hoffmann MM, Galeano BK, Mangalam A, Teixeiro E, White TA, Schrum AG, Cannon JF, Gil D. Nelson AD, et al. Among authors: cannon jf. Front Immunol. 2024 Aug 30;15:1434463. doi: 10.3389/fimmu.2024.1434463. eCollection 2024. Front Immunol. 2024. PMID: 39281668 Free PMC article.
Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.
Robins MJ, Nowak I, Rajwanshi VK, Miranda K, Cannon JF, Peterson MA, Andrei G, Snoeck R, De Clercq E, Balzarini J. Robins MJ, et al. Among authors: cannon jf. J Med Chem. 2007 Aug 9;50(16):3897-905. doi: 10.1021/jm070210n. Epub 2007 Jul 10. J Med Chem. 2007. PMID: 17622128
66 results