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Page 1
The cellular prion protein does not affect tau seeding and spreading of sarkosyl-insoluble fractions from Alzheimer's disease.
Sala-Jarque J, Gil V, Andrés-Benito P, Martínez-Soria I, Picón-Pagès P, Hernández F, Ávila J, Lanciego JL, Nuvolone M, Aguzzi A, Gavín R, Ferrer I, Del Río JA. Sala-Jarque J, et al. Among authors: lanciego jl. Sci Rep. 2024 Sep 16;14(1):21622. doi: 10.1038/s41598-024-72232-2. Sci Rep. 2024. PMID: 39284839 Free PMC article.
Investigation in the cannabigerol derivative VCE-003.2 as a disease-modifying agent in a mouse model of experimental synucleinopathy.
Burgaz S, Navarro E, Rodríguez-Carreiro S, Navarrete C, Garrido-Rodríguez M, Lastres-Becker I, Chocarro J, Lanciego JL, Muñoz E, Fernández-Ruiz J. Burgaz S, et al. Among authors: lanciego jl. Behav Brain Funct. 2024 Nov 1;20(1):28. doi: 10.1186/s12993-024-00256-9. Behav Brain Funct. 2024. PMID: 39487447 Free PMC article.
Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations.
Drouyer M, Merjane J, Nedelkoska T, Westhaus A, Scott S, Lee S, Burke PGR, McMullan S, Lanciego JL, Vicente AF, Bugallo R, Unzu C, González-Aseguinolaza G, Gonzalez-Cordero A, Lisowski L. Drouyer M, et al. Among authors: lanciego jl. Mol Ther Nucleic Acids. 2024 Jun 28;35(3):102264. doi: 10.1016/j.omtn.2024.102264. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39108635 Free PMC article.
Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates.
Córdoba KM, Jericó D, Jiang L, Collantes M, Alegre M, García-Ruiz L, Manzanilla O, Sampedro A, Herranz JM, Insausti I, Martinez de la Cuesta A, Urigo F, Alcaide P, Morán M, Martín MA, Lanciego JL, Lefebvre T, Gouya L, Quincoces G, Unzu C, Hervas-Stubbs S, Falcón-Pérez JM, Alegre E, Aldaz A, Fernández-Seara MA, Peñuelas I, Berraondo P, Martini PGV, Avila MA, Fontanellas A. Córdoba KM, et al. Among authors: lanciego jl. Gut. 2024 Nov 23:gutjnl-2024-332619. doi: 10.1136/gutjnl-2024-332619. Online ahead of print. Gut. 2024. PMID: 39366725 Free article.
Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles.
Bunuales M, Garduno A, Chillon M, Bosch A, Gonzalez-Aparicio M, Espelosin M, Garcia-Gomara M, Rico AJ, Garcia-Osta A, Cuadrado-Tejedor M, Lanciego JL, Hernandez-Alcoceba R. Bunuales M, et al. Among authors: lanciego jl. Gene Ther. 2024 Sep;31(9-10):455-466. doi: 10.1038/s41434-024-00466-w. Epub 2024 Jul 22. Gene Ther. 2024. PMID: 39039204 Free PMC article.
Boolean analysis shows a high proportion of dopamine D2 receptors interacting with adenosine A2A receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease.
Rivas-Santisteban R, Rico AJ, Muñoz A, Rodríguez-Pérez AI, Reyes-Resina I, Navarro G, Labandeira-García JL, Lanciego JL, Franco R. Rivas-Santisteban R, et al. Among authors: lanciego jl. Neurobiol Dis. 2023 Nov;188:106341. doi: 10.1016/j.nbd.2023.106341. Epub 2023 Oct 31. Neurobiol Dis. 2023. PMID: 37918757 Free article.
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome.
Ricobaraza A, Bunuales M, Gonzalez-Aparicio M, Fadila S, Rubinstein M, Vides-Urrestarazu I, Banderas J, Sola-Sevilla N, Sanchez-Carpintero R, Lanciego JL, Roda E, Honrubia A, Arnaiz P, Hernandez-Alcoceba R. Ricobaraza A, et al. Among authors: lanciego jl. J Mol Med (Berl). 2023 Dec;101(12):1587-1601. doi: 10.1007/s00109-023-02383-8. Epub 2023 Oct 11. J Mol Med (Berl). 2023. PMID: 37819378 Free PMC article.
Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates.
Chocarro J, Rico AJ, Ariznabarreta G, Roda E, Honrubia A, Collantes M, Peñuelas I, Vázquez A, Rodríguez-Pérez AI, Labandeira-García JL, Vila M, Lanciego JL. Chocarro J, et al. Among authors: lanciego jl. Brain. 2023 Dec 1;146(12):5000-5014. doi: 10.1093/brain/awad331. Brain. 2023. PMID: 37769648 Free PMC article.
137 results